| Literature DB >> 30090025 |
María Tereza Nieto-Coronel1,2, Allan David López-Vásquez1,2, Diana Marroquín-Flores1,2, Sandy Ruiz-Cruz1,2, Jorge Luis Martínez-Tláhuel1,3, Jaime De la Garza-Salazar1,3.
Abstract
Osteosarcoma is the most common primary malignancy of bone in children and young adults, the highest incidence peak is during adolescence and doesn't have any gender predominance. The main site of metastasis are the lungs and extrapulmonary cases are occasional. The incidence of metastasis in the Central Nervous System (CNS) is 2-6.5%, increase to 10-15% in patients with pulmonary metastases. Therefore, metastatic disease of the CNS is rare and the information on such patients is limited. Here, we describe a case of a 20-year old patient diagnosed with osteosarcoma in the left distal femur stage IIB, he developed pulmonary disease, during palliative chemotherapy experienced relapse to the brain classified as recursive partitioning analysis (RPA) class II, and was treated with external radiotherapy (30 Gy in 10 fractions) and later he had a poor evolution and died.Entities:
Keywords: Brain metastasis; Osteosarcoma; Radiation therapy
Year: 2018 PMID： 30090025 PMCID： PMC6078108 DOI： 10.1016/j.rpor.2018.06.003
Source DB: PubMed Journal: Rep Pract Oncol Radiother ISSN： 1507-1367