Literature DB >> 30089240

Translating In Vitro T Cell Metabolic Findings to In Vivo Tumor Models of Nutrient Competition.

Christopher Ecker1, James L Riley2.   

Abstract

Reductionist in vitro T cell assays have identified metabolic pathways critical for T cell function within the tumor microenvironment. We discuss the challenges of testing these concepts using in vivo tumor models.
Copyright © 2018 Elsevier Inc. All rights reserved.

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Year:  2018        PMID： 30089240      PMCID： PMC6463890          DOI： 10.1016/j.cmet.2018.07.009

Source DB:  PubMed          Journal:  Cell Metab        ISSN： 1550-4131            Impact factor:   27.287


  62 in total

Review 1.  Metabolic Barriers to T Cell Function in Tumors.

Authors:  Ayaka Sugiura; Jeffrey C Rathmell
Journal:  J Immunol       Date:  2018-01-15       Impact factor: 5.422

Review 2.  Mitochondrial metabolism in T cell activation and senescence: a mini-review.

Authors:  Noga Ron-Harel; Arlene H Sharpe; Marcia C Haigis
Journal:  Gerontology       Date:  2014-11-13       Impact factor: 5.140

Review 3.  Mitochondrial regulation of epigenetics and its role in human diseases.

Authors:  Sheroy Minocherhomji; Trygve O Tollefsbol; Keshav K Singh
Journal:  Epigenetics       Date:  2012-04-01       Impact factor: 4.528

4.  Foxp3 Reprograms T Cell Metabolism to Function in Low-Glucose, High-Lactate Environments.

Authors:  Alessia Angelin; Luis Gil-de-Gómez; Satinder Dahiya; Jing Jiao; Lili Guo; Matthew H Levine; Zhonglin Wang; William J Quinn; Piotr K Kopinski; Liqing Wang; Tatiana Akimova; Yujie Liu; Tricia R Bhatti; Rongxiang Han; Benjamin L Laskin; Joseph A Baur; Ian A Blair; Douglas C Wallace; Wayne W Hancock; Ulf H Beier
Journal:  Cell Metab       Date:  2017-04-13       Impact factor: 27.287

5.  T cell apoptosis by tryptophan catabolism.

Authors:  F Fallarino; U Grohmann; C Vacca; R Bianchi; C Orabona; A Spreca; M C Fioretti; P Puccetti
Journal:  Cell Death Differ       Date:  2002-10       Impact factor: 15.828

6.  In Situ Characterization of Tissue-Resident Immune Cells by MALDI Mass Spectrometry Imaging.

Authors:  Matthias Holzlechner; Katharina Strasser; Elitsa Zareva; Luise Steinhäuser; Hanna Birnleitner; Andrea Beer; Michael Bergmann; Rudolf Oehler; Martina Marchetti-Deschmann
Journal:  J Proteome Res       Date:  2016-11-03       Impact factor: 4.466

7.  Absolute Quantification of Matrix Metabolites Reveals the Dynamics of Mitochondrial Metabolism.

Authors:  Walter W Chen; Elizaveta Freinkman; Tim Wang; Kıvanç Birsoy; David M Sabatini
Journal:  Cell       Date:  2016-08-25       Impact factor: 41.582

8.  Glucose uptake is limiting in T cell activation and requires CD28-mediated Akt-dependent and independent pathways.

Authors:  Sarah R Jacobs; Catherine E Herman; Nancie J Maciver; Jessica A Wofford; Heather L Wieman; Jeremy J Hammen; Jeffrey C Rathmell
Journal:  J Immunol       Date:  2008-04-01       Impact factor: 5.422

9.  Indoleamine 2,3-dioxygenase regulates anti-tumor immunity in lung cancer by metabolic reprogramming of immune cells in the tumor microenvironment.

Authors:  Cara C Schafer; Yong Wang; Kenneth P Hough; Anandi Sawant; Stefan C Grant; Victor J Thannickal; Jaroslaw Zmijewski; Selvarangan Ponnazhagan; Jessy S Deshane
Journal:  Oncotarget       Date:  2016-11-15

10.  The Proteomic Landscape of Human Ex Vivo Regulatory and Conventional T Cells Reveals Specific Metabolic Requirements.

Authors:  Claudio Procaccini; Fortunata Carbone; Dario Di Silvestre; Francesca Brambilla; Veronica De Rosa; Mario Galgani; Deriggio Faicchia; Gianni Marone; Donatella Tramontano; Marco Corona; Carlo Alviggi; Antonio Porcellini; Antonio La Cava; Pierluigi Mauri; Giuseppe Matarese
Journal:  Immunity       Date:  2016-02-16       Impact factor: 31.745
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  7 in total

1.  Glucose metabolism inhibitor PFK-015 combined with immune checkpoint inhibitor is an effective treatment regimen in cancer.

Authors:  Jia Bo Zheng; Chau Wei Wong; Jia Liu; Xiao-Jing Luo; Wei-Yi Zhou; Yan-Xing Chen; Hui-Yan Luo; Zhao-Lei Zeng; Chao Ren; Xiao-Ming Xie; De-Shen Wang
Journal:  Oncoimmunology       Date:  2022-05-25       Impact factor: 7.723

Review 2.  Immunometabolism and HIV-1 pathogenesis: food for thought.

Authors:  Asier Sáez-Cirión; Irini Sereti
Journal:  Nat Rev Immunol       Date:  2020-08-06       Impact factor: 53.106

Review 3.  Genetic engineering of T cells for immunotherapy.

Authors:  Gavin I Ellis; Neil C Sheppard; James L Riley
Journal:  Nat Rev Genet       Date:  2021-02-18       Impact factor: 59.581

4.  Accumulation of long-chain fatty acids in the tumor microenvironment drives dysfunction in intrapancreatic CD8+ T cells.

Authors:  Teresa Manzo; Boone M Prentice; Kristin G Anderson; Ayush Raman; Aislyn Schalck; Gabriela S Codreanu; Carina B Nava Lauson; Silvia Tiberti; Andrea Raimondi; Marissa A Jones; Michelle Reyzer; Breanna M Bates; Jeffrey M Spraggins; Nathan H Patterson; John A McLean; Kunal Rai; Carlo Tacchetti; Sara Tucci; Jennifer A Wargo; Simona Rodighiero; Karen Clise-Dwyer; Stacy D Sherrod; Michael Kim; Nicholas E Navin; Richard M Caprioli; Philip D Greenberg; Giulio Draetta; Luigi Nezi
Journal:  J Exp Med       Date:  2020-08-03       Impact factor: 14.307

5.  Quantification of microenvironmental metabolites in murine cancers reveals determinants of tumor nutrient availability.

Authors:  Mark R Sullivan; Laura V Danai; Caroline A Lewis; Sze Ham Chan; Dan Y Gui; Tenzin Kunchok; Emily A Dennstedt; Matthew G Vander Heiden; Alexander Muir
Journal:  Elife       Date:  2019-04-16       Impact factor: 8.140

Review 6.  Targeting T Cell Metabolism in Inflammatory Skin Disease.

Authors:  Leonhard von Meyenn; Nicole Leonie Bertschi; Christoph Schlapbach
Journal:  Front Immunol       Date:  2019-09-24       Impact factor: 7.561

Review 7.  CAR Talk: How Cancer-Specific CAR T Cells Can Instruct How to Build CAR T Cells to Cure HIV.

Authors:  Gloria B Kim; Kristen Hege; James L Riley
Journal:  Front Immunol       Date:  2019-09-27       Impact factor: 7.561
  7 in total

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