Literature DB >> 30088934

Eucalyptusdimers A-C, Dimeric Phloroglucinol-Phellandrene Meroterpenoids from Eucalyptus robusta.

Xu-Jie Qin1, Mi-Yan Feng1, Hui Liu1, Wei Ni1, Tyler Rauwolf2, John A Porco2, Huan Yan1, Li He3, Hai-Yang Liu1.   

Abstract

Eucalyptusdimers A-C, three dimeric phellandrene-derived meroterpenoids featuring an unprecedented, fused skeleton between two phellandrene and two acylphloroglucinol subunits, along with one biogenetically related intermediate, (±)-eucalyprobusone A, were isolated from the fruits of Eucalyptus robusta. Their structures and absolute configurations were elucidated using spectroscopic data, X-ray crystallography, and electronic circular dichroism analysis. The isolated meroterpenoids were evaluated for their anti-inflammatory, acetylcholinesterase inhibitory, and protein tyrosine phosphatase 1B inhibitory effects.

Entities:  

Year:  2018        PMID： 30088934      PMCID： PMC6132224          DOI： 10.1021/acs.orglett.8b02259

Source DB:  PubMed          Journal:  Org Lett        ISSN： 1523-7052            Impact factor:   6.005


  13 in total

1.  Eucalyptals A-C with a new skeleton isolated from Eucalyptus globulus.

Authors:  Sheng Yin; Jun-Juan Xue; Cheng-Qi Fan; Ze-Hong Miao; Jian Ding; Jian-Min Yue
Journal:  Org Lett       Date:  2007-11-17       Impact factor: 6.005

2.  Biomimetic Syntheses of Callistrilones A-E via an Oxidative [3 + 2] Cycloaddition.

Authors:  Yonghong Guo; Yuhan Zhang; Mingxing Xiao; Zhixiang Xie
Journal:  Org Lett       Date:  2018-04-16       Impact factor: 6.005

3.  (1) H NMR-Guided Isolation of Formyl-Phloroglucinol Meroterpenoids from the Leaves of Eucalyptus robusta.

Authors:  Zhi-Chun Shang; Ming-Hua Yang; Kai-Li Jian; Xiao-Bing Wang; Ling-Yi Kong
Journal:  Chemistry       Date:  2016-07-14       Impact factor: 5.236

4.  Potent HGF/c-Met axis inhibitors from Eucalyptus globulus: the coupling of phloroglucinol and sesquiterpenoid is essential for the activity.

Authors:  Sheng-Ping Yang; Xiao-Wei Zhang; Jing Ai; Li-She Gan; Jin-Biao Xu; Ying Wang; Zu-Shang Su; Lu Wang; Jian Ding; Mei-Yu Geng; Jian-Min Yue
Journal:  J Med Chem       Date:  2012-09-07       Impact factor: 7.446

5.  A short biomimetic synthesis of the meroterpenoids guajadial and psidial A.

Authors:  Andrew L Lawrence; Robert M Adlington; Jack E Baldwin; Victor Lee; Jessica A Kershaw; Amber L Thompson
Journal:  Org Lett       Date:  2010-04-16       Impact factor: 6.005

6.  Meroterpenoids with Antitumor Activities from Guava (Psidium guajava).

Authors:  Xu-Jie Qin; Qian Yu; Huan Yan; Afsar Khan; Mi-Yan Feng; Pan-Pan Li; Xiao-Jiang Hao; Lin-Kun An; Hai-Yang Liu
Journal:  J Agric Food Chem       Date:  2017-06-09       Impact factor: 5.279

7.  Eucarobustols A-I, Conjugates of Sesquiterpenoids and Acylphloroglucinols from Eucalyptus robusta.

Authors:  Yang Yu; Li-She Gan; Sheng-Ping Yang; Li Sheng; Qun-Fang Liu; Shao-Nong Chen; Jia Li; Jian-Min Yue
Journal:  J Nat Prod       Date:  2016-05-04       Impact factor: 4.050

8.  Cytotoxic Meroterpenoids with Rare Skeletons from Psidium guajava Cultivated in Temperate Zone.

Authors:  Xu-Jie Qin; Huan Yan; Wei Ni; Mu-Yuan Yu; Afsar Khan; Hui Liu; Hong-Xia Zhang; Li He; Xiao-Jiang Hao; Ying-Tong Di; Hai-Yang Liu
Journal:  Sci Rep       Date:  2016-09-02       Impact factor: 4.379

9.  New Formyl Phloroglucinol Meroterpenoids from the Leaves of Eucalyptus robusta.

Authors:  Zhi-Chun Shang; Ming-Hua Yang; Rui-Huan Liu; Xiao-Bing Wang; Ling-Yi Kong
Journal:  Sci Rep       Date:  2016-12-22       Impact factor: 4.379

10.  Cytotoxic Acylphloroglucinol Derivatives from Callistemon salignus.

Authors:  Xu-Jie Qin; Tong Shu; Qian Yu; Huan Yan; Wei Ni; Lin-Kun An; Pan-Pan Li; Yin-E Zhi; Afsar Khan; Hai-Yang Liu
Journal:  Nat Prod Bioprospect       Date:  2017-06-15
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  6 in total

Review 1.  Biological activities of meroterpenoids isolated from different sources.

Authors:  Neeraj Kumar Fuloria; Radhika K Raheja; Kaushal H Shah; Manisha J Oza; Yogesh A Kulkarni; Vetriselvan Subramaniyan; Mahendran Sekar; Shivkanya Fuloria
Journal:  Front Pharmacol       Date:  2022-09-19       Impact factor: 5.988

2.  Quantification and Localization of Formylated Phloroglucinol Compounds (FPCs) in Eucalyptus Species.

Authors:  Bruna Marques Dos Santos; Juliane F S Zibrandtsen; Disan Gunbilig; Mette Sørensen; Federico Cozzi; Berin A Boughton; Allison Maree Heskes; Elizabeth Heather Jakobsen Neilson
Journal:  Front Plant Sci       Date:  2019-02-26       Impact factor: 5.753

3.  Interaction of Natural Compounds in Licorice and Turmeric with HIV-NCp7 Zinc Finger Domain: Potential Relevance to the Mechanism of Antiviral Activity.

Authors:  Runjing Wang; Yinyu Wei; Meiqin Wang; Pan Yan; Hongliang Jiang; Zhifeng Du
Journal:  Molecules       Date:  2021-06-10       Impact factor: 4.411

Review 4.  Meroterpenoids: A Comprehensive Update Insight on Structural Diversity and Biology.

Authors:  Mamona Nazir; Muhammad Saleem; Muhammad Imran Tousif; Muhammad Aijaz Anwar; Frank Surup; Iftikhar Ali; Daijie Wang; Nilufar Z Mamadalieva; Elham Alshammari; Mohamed L Ashour; Ahmed M Ashour; Ishtiaq Ahmed; Ivan R Green; Hidayat Hussain
Journal:  Biomolecules       Date:  2021-06-29

5.  Structurally Diverse Polymethylated Phloroglucinol Meroterpenoids from Baeckea frutescens.

Authors:  Yin-E Zhi; Xu-Jie Qi; Hui Liu; Yuan Zeng; Wei Ni; Li He; Zu-Ding Wang; Hai-Yang Liu
Journal:  Nat Prod Bioprospect       Date:  2018-10-29

6.  HPLC-PDA-ESI-MS/MS Profiling and Anti-Biofilm Potential of Eucalyptussideroxylon Flowers.

Authors:  Mona M Okba; Riham A El-Shiekh; Mohammed Abu-Elghait; Mansour Sobeh; Rehab M S Ashour
Journal:  Antibiotics (Basel)       Date:  2021-06-23
  6 in total

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