| Literature DB >> 30087152 |
Giulia Ceglie1, Giulia Macchiarulo1, Maria Rosaria Marchili2, Alessandra Marchesi2, Lelia Rotondi Aufiero2, Chiara Di Camillo2, Alberto Villani2.
Abstract
We report three cases of scurvy in previously healthy children referred to us for leg pain and refusal to walk. All children had no significant medical history, symptoms had started months before and subtly advanced. Two of them presented with gingival hyperplasia and petechiae, another one reported night sweats and gingival bleeding in the past few weeks. Two had vitamin D deficiency, and all had microcytic anaemia (in one case requiring transfusional support). A nutritional screening revealed low or undetectable levels of ascorbic acid. This, along with the clinical and radiological findings, led to a diagnosis of scurvy. Vitamin C supplementation was started with rapid improvement of the children's clinical condition. Scurvy is a rare disease in the 'first world', but there are anecdotal reports of scurvy in children without any of the known risk factors for this condition. In our cases, a selective diet was the only risk factor. © Author(s) (or their employer(s)) 2019. No commercial re-use. See rights and permissions. Published by BMJ.Entities:
Keywords: collagen disorders; general paediatrics; growth; nutrition; obesity
Year: 2018 PMID: 30087152 DOI: 10.1136/archdischild-2018-315496
Source DB: PubMed Journal: Arch Dis Child ISSN: 0003-9888 Impact factor: 3.791