Diffuse cutaneous hypersensitivity reaction after dexamethasone/polymyxin B/neomycin combination eyedrops.

Localized cutaneous hypersensitivity reactions to antibiotic eyedrops are not unusual. To our knowledge, however, a diffuse cutaneous reaction to eyedrops containing dexamethasone/polymyxin B/neomycin has never been reported. We describe the diffuse skin changes noted in a 72-year-old patient five days after starting eyedrop therapy.