| Literature DB >> 30085268 |
Christopher B Eke1, Robin A Brown2, Ronalda J De Lacy1, Komala Pillay3, Elizabeth A Goddard1.
Abstract
Collagenous gastritis is an uncommon gastrointestinal disease in children. Its cause remains uncertain. It may present as severe hypoproteinaemia manifesting as generalized oedema. We report a 15 months old female who presented with pica, generalized body oedema and diarrhoea. Diagnostic workup revealed gastric replacement of the lamina propria by hyalinized collagen on histology. This case seeks to highlight the need for early paediatric gastroenterology referral including oesophagogastroduodenoscopy with multiple tissue biopsies as part of a broad diagnostic workup in children with non-specific gastrointestinal symptoms to improve diagnostic yield and enable accurate histologic diagnosis, so that appropriate therapy can be timeously applied.Entities:
Keywords: Collagenous gastritis; child; histopathology; oesophagogastroduodenoscopy
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Year: 2019 PMID: 30085268 DOI: 10.1093/tropej/fmy048
Source DB: PubMed Journal: J Trop Pediatr ISSN: 0142-6338 Impact factor: 1.165