Literature DB >> 30085268

Collagenous gastritis: An unusual cause of generalized oedema in a child.

Christopher B Eke1, Robin A Brown2, Ronalda J De Lacy1, Komala Pillay3, Elizabeth A Goddard1.   

Abstract

Collagenous gastritis is an uncommon gastrointestinal disease in children. Its cause remains uncertain. It may present as severe hypoproteinaemia manifesting as generalized oedema. We report a 15 months old female who presented with pica, generalized body oedema and diarrhoea. Diagnostic workup revealed gastric replacement of the lamina propria by hyalinized collagen on histology. This case seeks to highlight the need for early paediatric gastroenterology referral including oesophagogastroduodenoscopy with multiple tissue biopsies as part of a broad diagnostic workup in children with non-specific gastrointestinal symptoms to improve diagnostic yield and enable accurate histologic diagnosis, so that appropriate therapy can be timeously applied.
© The Author(s) [2018]. Published by Oxford University Press. All rights reserved. For permissions, please email: journals.permissions@oup.com.

Entities:  

Keywords:  Collagenous gastritis; child; histopathology; oesophagogastroduodenoscopy

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Year:  2019        PMID: 30085268     DOI: 10.1093/tropej/fmy048

Source DB:  PubMed          Journal:  J Trop Pediatr        ISSN: 0142-6338            Impact factor:   1.165


  1 in total

1.  Collagenous Gastritis in Children: Incidence, Disease Course, and Associations With Autoimmunity and Inflammatory Markers.

Authors:  Timo Käppi; Alkwin Wanders; Mats Wolving; Christine Lingblom; Birgitta Davidsson Bården; Rikard Arkel; Josefine Hätting; Johan Anderzén; Christine Wennerås; Robert Saalman
Journal:  Clin Transl Gastroenterol       Date:  2020-08       Impact factor: 4.396

  1 in total

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