Literature DB >> 30084808

Maslinic acid as an effective anticancer agent.

Xiukun Lin1, Ulku Ozbey2, Uteuliyev Yerzhan Sabitaliyevich3, Rukset Attar4, Beraat Ozcelik5, Yuanyan Zhang1, Mingyue Guo1, Minghua Liu1, Saleh S Alhewairini6, Ammad Ahmad Farooqi7.   

Abstract

Maslinic acid (2α,3β-dihydroxyolean-12-en-28-oic acid) is a naturally occurring pentacyclic triterpenic compound. Maslinic acid is gradually gaining attention as an excellent pharmacologically active product because of its premium biological properties. In this review we will focus on chemopreventive properties of Maslinic acid against different cancers. Seemingly, available data is limited and we have yet to unravel how Maslinic acid therapeutically targeted oncogenic cell signal transduction cascades in different cancers. Moreover, there are visible knowledge gaps about the ability of Maslinic acid to modulate oncogenic and tumor suppressor microRNAs in various cancers.

Entities:  

Keywords:  Apoptosis; Cancer; Maslinic Acid.; Signaling

Mesh：

Substances：

Year:  2018        PMID： 30084808

Source DB:  PubMed          Journal:  Cell Mol Biol (Noisy-le-grand)        ISSN： 0145-5680            Impact factor:   1.770


  5 in total

1.  Phytochemical profile, antioxidant, antiproliferative, and enzyme inhibition-docking analyses of Salvia ekimiana Celep & Doğan.

Authors:  Gökçe Şeker Karatoprak; Fatih Göger; İsmail Çelik; Ümit Budak; Esra Küpeli Akkol; Michael Aschner
Journal:  S Afr J Bot       Date:  2021-10-09       Impact factor: 2.315

2.  Assessment of the Antiangiogenic and Anti-Inflammatory Properties of a Maslinic Acid Derivative and its Potentiation using Zinc Chloride.

Authors:  Ioana Zinuca Pavel; Rene Csuk; Corina Danciu; Stefana Avram; Flavia Baderca; Andreea Cioca; Elena-Alina Moacă; Ciprian-Valentin Mihali; Iulia Pinzaru; Danina Mirela Muntean; Cristina Adriana Dehelean
Journal:  Int J Mol Sci       Date:  2019-06-10       Impact factor: 5.923

3.  Analysis of the Mechanism of Maslinic Acid on Papillary Thyroid Carcinoma Based on RNA-Seq Technology.

Authors:  Rong Li; Yanjiao Zhang; Runqing Xiang; Aihe Lin; Zongxiao Xia; Xiaomei Long; Shuang Guo; Yuan Fan; Zukun Chen
Journal:  Evid Based Complement Alternat Med       Date:  2022-09-07       Impact factor: 2.650

Review 4.  Semisynthetic Derivatives of Pentacyclic Triterpenes Bearing Heterocyclic Moieties with Therapeutic Potential.

Authors:  Gabriela Nistor; Cristina Trandafirescu; Alexandra Prodea; Andreea Milan; Andreea Cristea; Roxana Ghiulai; Roxana Racoviceanu; Alexandra Mioc; Marius Mioc; Viviana Ivan; Codruța Șoica
Journal:  Molecules       Date:  2022-10-03       Impact factor: 4.927

5.  Synthesis and Biological Activity of Triterpene-Coumarin Conjugates.

Authors:  Karina Vega-Granados; Marta Medina-O'Donnell; Francisco Rivas; Fernando J Reyes-Zurita; Antonio Martinez; Luis Alvarez de Cienfuegos; Jose A Lupiañez; Andres Parra
Journal:  J Nat Prod       Date:  2021-05-06       Impact factor: 4.050
  5 in total

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