Kohta Fujiwara1,2,3, Miho Yasuda2, Jun Hata1,4, Yuji Oshima2, Sawako Hashimoto1,2, Takeshi Yoshitomi3, Yutaka Kiyohara5, Tatsuro Ishibashi2, Toshiharu Ninomiya1,4, Koh-Hei Sonoda2. 1. a Department of Epidemiology and Public Health , Graduate School of Medical Sciences, Kyushu University , Fukuoka , Japan. 2. b Department of Ophthalmology, Graduate School of Medical Sciences , Kyushu University , Fukuoka , Japan. 3. c Department of Ophthalmology, Graduate School of Medical Sciences , Akita University , Akita , Japan. 4. d Center for Cohort Studies, Graduate School of Medical Sciences , Kyushu University , Fukuoka , Japan. 5. e Hisayama Research Institute for Lifestyle Diseases , Fukuoka , Japan.
Abstract
PURPOSE: To estimate the prevalence and risk factors for polypoidal choroidal vasculopathy (PCV) in a general Japanese population. METHODS: This population-based, cross-sectional study was conducted in 2007 with subjects from the Hisayama Study. Of the 3,648 residents in Hisayama, Japan, 2,663 who were ≥ 50 years old were enrolled in this study. The characteristics of PCV were determined by fundus examination or based on indocyanine green and fluorescein angiographic findings. We evaluated the contributions of the risk factors for PCV. RESULTS: Among the 207 participants with age-related macular degeneration (AMD), 174 (6.5%) had early AMD, and 33 (1.2%) had late AMD, including 10 participants with PCV (0.4%). Male and smoking habit were significant risk factors for the development of PCV. CONCLUSIONS: The prevalence of PCV is higher among Japanese subjects than Caucasians in Western countries. Male gender and smoking habit were significant risk factors for PCV in a general Japanese population.
PURPOSE: To estimate the prevalence and risk factors for polypoidal choroidal vasculopathy (PCV) in a general Japanese population. METHODS: This population-based, cross-sectional study was conducted in 2007 with subjects from the Hisayama Study. Of the 3,648 residents in Hisayama, Japan, 2,663 who were ≥ 50 years old were enrolled in this study. The characteristics of PCV were determined by fundus examination or based on indocyanine green and fluorescein angiographic findings. We evaluated the contributions of the risk factors for PCV. RESULTS: Among the 207 participants with age-related macular degeneration (AMD), 174 (6.5%) had early AMD, and 33 (1.2%) had late AMD, including 10 participants with PCV (0.4%). Male and smoking habit were significant risk factors for the development of PCV. CONCLUSIONS: The prevalence of PCV is higher among Japanese subjects than Caucasians in Western countries. Male gender and smoking habit were significant risk factors for PCV in a general Japanese population.
Authors: Beau J Fenner; Chui Ming Gemmy Cheung; Shaun S Sim; Won Ki Lee; Giovanni Staurenghi; Timothy Y Y Lai; Paisan Ruamviboonsuk; Gregg Kokame; Yasuo Yanagi; Kelvin Y C Teo Journal: Eye (Lond) Date: 2021-07-14 Impact factor: 3.775