Literature DB >> 30084105

Saturated Fat: Part of a Healthy Diet.

Victoria M Gershuni1,2.   

Abstract

PURPOSE OF REVIEW: Despite the American public following recommendations to decrease absolute dietary fat intake and specifically decrease saturated fat intake, we have seen a dramatic rise over the past 40 years in the rates of non-communicable diseases associated with obesity and overweight, namely cardiovascular disease. The development of the diet-heart hypothesis in the mid twentieth century led to faulty but long-held beliefs that dietary intake of saturated fat led to heart disease. Saturated fat can lead to increased LDL cholesterol levels, and elevated plasma cholesterol levels have been shown to be a risk factor for cardiovascular disease; however, the correlative nature of their association does not assign causation. RECENT
FINDINGS: Advances in understanding the role of various lipoprotein particles and their atherogenic risk have been helpful for understanding how different dietary components may impact CVD risk. Numerous meta-analyses and systematic reviews of both the historical and current literature reveals that the diet-heart hypothesis was not, and still is not, supported by the evidence. There appears to be no consistent benefit to all-cause or CVD mortality from the reduction of dietary saturated fat. Further, saturated fat has been shown in some cases to have an inverse relationship with obesity-related type 2 diabetes. Rather than focus on a single nutrient, the overall diet quality and elimination of processed foods, including simple carbohydrates, would likely do more to improve CVD and overall health. It is in the best interest of the American public to clarify dietary guidelines to recognize that dietary saturated fat is not the villain we once thought it was.

Entities:  

Keywords:  Atherosclerosis; CVD; Cardiovascular disease; Diet; Diet-heart hypothesis; Dietary fat; Dietary guidelines; Fatty acids; LDL cholesterol; PUFA; SFA; Saturated fat; Triglycerides

Mesh:

Substances:

Year:  2018        PMID: 30084105     DOI: 10.1007/s13668-018-0238-x

Source DB:  PubMed          Journal:  Curr Nutr Rep        ISSN: 2161-3311


  106 in total

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2.  Introduction to the special focus issue on the impact of diet on gut microbiota composition and function and future opportunities for nutritional modulation of the gut microbiome to improve human health.

Authors:  Sharon M Donovan
Journal:  Gut Microbes       Date:  2017-02-28

Review 3.  Short- and medium-chain fatty acids in energy metabolism: the cellular perspective.

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Journal:  J Lipid Res       Date:  2016-04-14       Impact factor: 5.922

Review 4.  Saturated fats: what dietary intake?

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Journal:  Am J Clin Nutr       Date:  2004-09       Impact factor: 7.045

Review 5.  A review of fatty acid profiles and antioxidant content in grass-fed and grain-fed beef.

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Journal:  Nutr J       Date:  2010-03-10       Impact factor: 3.271

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Journal:  Altern Med Rev       Date:  2007-09

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Journal:  Am J Clin Nutr       Date:  1976-12       Impact factor: 7.045

9.  Plasma phospholipid fatty acid concentration and incident coronary heart disease in men and women: the EPIC-Norfolk prospective study.

Authors:  Kay-Tee Khaw; Marlin D Friesen; Elio Riboli; Robert Luben; Nicholas Wareham
Journal:  PLoS Med       Date:  2012-07-03       Impact factor: 11.069

10.  Dietary emulsifiers impact the mouse gut microbiota promoting colitis and metabolic syndrome.

Authors:  Benoit Chassaing; Omry Koren; Julia K Goodrich; Angela C Poole; Shanthi Srinivasan; Ruth E Ley; Andrew T Gewirtz
Journal:  Nature       Date:  2015-02-25       Impact factor: 49.962

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Authors:  Cielo García-Montero; Oscar Fraile-Martínez; Ana M Gómez-Lahoz; Leonel Pekarek; Alejandro J Castellanos; Fernando Noguerales-Fraguas; Santiago Coca; Luis G Guijarro; Natalio García-Honduvilla; Angel Asúnsolo; Lara Sanchez-Trujillo; Guillermo Lahera; Julia Bujan; Jorge Monserrat; Melchor Álvarez-Mon; Miguel A Álvarez-Mon; Miguel A Ortega
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Review 5.  Effect of Dietary Fatty Acids on MicroRNA Expression Related to Metabolic Disorders and Inflammation in Human and Animal Trials.

Authors:  Karla MacDonald-Ramos; Alejandra Martínez-Ibarra; Adriana Monroy; Juan Miranda-Ríos; Marco Cerbón
Journal:  Nutrients       Date:  2021-05-27       Impact factor: 5.717

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