BACKGROUND: Fully-covered, self-expandable metal stents (FCSEMS) have been deployed to treat symptomatic chronic pancreatitis (CP) complicated with main pancreatic duct (MPD) stricture. Although this strategy can be effective, it has the disadvantages of stent migration or stent-induced ductal change. Removal of an FCSEMS can also be challenging in the face of distal migration because of MPD stricture. Dumbbell-type FCSEMS have been developed to prevent stent-induced ductal changes and improve removability when treating benign biliary stricture. This stent might also confer clinical benefits upon patients with MPD stricture. AIMS: The present pilot study aimed to determine the feasibility and safety of deploying dumbbell-type FCSEMS in patients with CP complicated by MPD stricture. METHOD: Stents were deployed in 22 patients with MPD stricture caused by CP and complicated by abdominal pain. RESULTS: Strictures were located at the head (n = 19), body (n = 2), and head and tail (n = 1) of the MPD. Stents were deployed above the papilla in three patients. All stents were deployed for a median duration of 142 (range, 49-190) days and removed. The resolution of MPD strictures was confirmed by pancreatography in 19 (86.3%) patients. Two metal stents that spontaneously tore during removal from two patients had otherwise functioned normally. Only three patients developed recurrent MPD stricture during a median follow-up of 419 (range, 261-484) days.. CONCLUSIONS: Deployment of a dumbbell-type FCSEMS seems feasible for MPD stricture, and the rate of adverse events is acceptable.
BACKGROUND: Fully-covered, self-expandable metal stents (FCSEMS) have been deployed to treat symptomatic chronic pancreatitis (CP) complicated with main pancreatic duct (MPD) stricture. Although this strategy can be effective, it has the disadvantages of stent migration or stent-induced ductal change. Removal of an FCSEMS can also be challenging in the face of distal migration because of MPD stricture. Dumbbell-type FCSEMS have been developed to prevent stent-induced ductal changes and improve removability when treating benign biliary stricture. This stent might also confer clinical benefits upon patients with MPD stricture. AIMS: The present pilot study aimed to determine the feasibility and safety of deploying dumbbell-type FCSEMS in patients with CP complicated by MPD stricture. METHOD: Stents were deployed in 22 patients with MPD stricture caused by CP and complicated by abdominal pain. RESULTS: Strictures were located at the head (n = 19), body (n = 2), and head and tail (n = 1) of the MPD. Stents were deployed above the papilla in three patients. All stents were deployed for a median duration of 142 (range, 49-190) days and removed. The resolution of MPD strictures was confirmed by pancreatography in 19 (86.3%) patients. Two metal stents that spontaneously tore during removal from two patients had otherwise functioned normally. Only three patients developed recurrent MPD stricture during a median follow-up of 419 (range, 261-484) days.. CONCLUSIONS: Deployment of a dumbbell-type FCSEMS seems feasible for MPD stricture, and the rate of adverse events is acceptable.
Authors: Peter B Cotton; Glenn M Eisen; Lars Aabakken; Todd H Baron; Matt M Hutter; Brian C Jacobson; Klaus Mergener; Albert Nemcek; Bret T Petersen; John L Petrini; Irving M Pike; Linda Rabeneck; Joseph Romagnuolo; John J Vargo Journal: Gastrointest Endosc Date: 2010-03 Impact factor: 9.427
Authors: Jacques Devière; D Nageshwar Reddy; Andreas Püspök; Thierry Ponchon; Marco J Bruno; Michael J Bourke; Horst Neuhaus; André Roy; Ferrán González-Huix Lladó; Alan N Barkun; Paul P Kortan; Claudio Navarrete; Joyce Peetermans; Daniel Blero; Sundeep Lakhtakia; Werner Dolak; Vincent Lepilliez; Jan W Poley; Andrea Tringali; Guido Costamagna Journal: Gastroenterology Date: 2014-05-04 Impact factor: 22.682
Authors: Djuna L Cahen; Dirk J Gouma; Yung Nio; Erik A J Rauws; Marja A Boermeester; Olivier R Busch; Jaap Stoker; Johan S Laméris; Marcel G W Dijkgraaf; Kees Huibregtse; Marco J Bruno Journal: N Engl J Med Date: 2007-02-15 Impact factor: 91.245
Authors: G Costamagna; M Bulajic; A Tringali; M Pandolfi; A Gabbrielli; C Spada; L Petruzziello; P Familiari; M Mutignani Journal: Endoscopy Date: 2006-03 Impact factor: 10.093