Literature DB >> 3008329

Receptor-associated resistance to growth hormone-releasing factor in dwarf "little" mice.

J O Jansson, T R Downs, W G Beamer, L A Frohman.   

Abstract

Anterior pituitaries from the dwarf mouse strain "little" did not release growth hormone or accumulate adenosine 3',5'-monophosphate (cyclic AMP) in response to human and rat growth hormone-releasing factor (GRF). Dibutyryl cyclic AMP, as well as the adenylate cyclase stimulators forskolin and cholera toxin, markedly stimulated growth hormone (GH) release. The basis of the GH deficiency in the little mouse may therefore be a defect in an early stage of GRF-stimulated GH release related either to receptor binding or to the function of the hormone-receptor complex.

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Year:  1986        PMID： 3008329     DOI： 10.1126/science.3008329

Source DB:  PubMed          Journal:  Science        ISSN： 0036-8075            Impact factor:   47.728


  19 in total

1.  Sex differences in thrombosis in mice are mediated by sex-specific growth hormone secretion patterns.

Authors:  Joshua H Wong; Jonathan Dukes; Robert E Levy; Brandon Sos; Sara E Mason; Tina S Fong; Ethan J Weiss
Journal:  J Clin Invest       Date:  2008-08       Impact factor: 14.808

Review 2.  The role of liver-derived insulin-like growth factor-I.

Authors:  Claes Ohlsson; Subburaman Mohan; Klara Sjögren; Asa Tivesten; Jörgen Isgaard; Olle Isaksson; John-Olov Jansson; Johan Svensson
Journal:  Endocr Rev       Date:  2009-07-09       Impact factor: 19.871

3.  Immunofluorescent analysis of somatotroph distribution in the adenohypophysis of developing lit/lit mice.

Authors:  D B Wilson; D P Wyatt
Journal:  J Anat       Date:  1988-02       Impact factor: 2.610

4.  Tissue-specific gene expression in mouse hepatocytes cultured in growth-restricting medium.

Authors:  T Spiegelberg; J O Bishop
Journal:  Mol Cell Biol       Date:  1988-08       Impact factor: 4.272

5.  Abrogation of growth hormone secretion rescues fatty liver in mice with hepatocyte-specific deletion of JAK2.

Authors:  Brandon C Sos; Charles Harris; Sarah M Nordstrom; Jennifer L Tran; Mercedesz Balázs; Patrick Caplazi; Maria Febbraio; Milana A B Applegate; Kay-Uwe Wagner; Ethan J Weiss
Journal:  J Clin Invest       Date:  2011-04       Impact factor: 14.808

Review 6.  Growth Hormone Releasing Hormone (GHRH) and the GHRH Receptor.

Authors:  Karen Lin-Su; Michael P Wajnrajch
Journal:  Rev Endocr Metab Disord       Date:  2002-12       Impact factor: 6.514

7.  Growth hormone enhances hepatic epidermal growth factor receptor concentration in mice.

Authors:  J O Jansson; S Ekberg; S B Hoath; W G Beamer; L A Frohman
Journal:  J Clin Invest       Date:  1988-12       Impact factor: 14.808

8.  Antagonism of endogenous growth hormone-releasing hormone (GHRH) leads to reduced proliferation and apoptosis in MDA231 breast cancer cells.

Authors:  Philip Zeitler; Gamini Siriwardana
Journal:  Endocrine       Date:  2002-06       Impact factor: 3.633

9.  Regulation of insulin-like growth factor I gene expression by growth hormone.

Authors:  L S Mathews; G Norstedt; R D Palmiter
Journal:  Proc Natl Acad Sci U S A       Date:  1986-12       Impact factor: 11.205

Review 10.  The role of endocrine insulin-like growth factor-I and insulin in breast cancer.

Authors:  Danielle Lann; Derek LeRoith
Journal:  J Mammary Gland Biol Neoplasia       Date:  2008-11-22       Impact factor: 2.673
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