Literature DB >> 30083074

Kala-Azar and leukemia: A rare association.

Ali Bay1, Elif Habibe Aktekin1, Fahriye Ekşi2, Murat Özcan3.   

Abstract

Visceral leishmaniasis is an infectious disease that infects and multiplies in macrophages of the liver, spleen, and bone marrow. The most common clinical features are fever, splenomegaly, and anemia. Anemia, leucopenia, and thrombocytopenia are the main hematologic abnormalities commonly seen in visceral leishmaniasis. These findings can be seen in several types of hematologic disorders. The findings are similar to most hematologic disorders and so may make diagnosis problematic. It is difficult to confirm when it is seen except in epidemiologic areas. It can be fatal if it is not treated and appropriate treatment can be lifesaving. In this article a 12 year-old male patient who was followed-up with diagnosis of acute lymphoblastic leukemia and received maintenance therapy while being under remission after BFM-ALL-2000 treatment protocol and diagnosed with hemophagocytic lymphohistiocytosis due to Kala-azar during this period was presented.

Entities:  

Keywords:  Leukemia; pancytopenia; visceral leishmaniasis

Year:  2018        PMID: 30083074      PMCID: PMC6070223          DOI: 10.5152/TurkPediatriArs.2018.3590

Source DB:  PubMed          Journal:  Turk Pediatri Ars


  6 in total

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Journal:  Eur Rev Med Pharmacol Sci       Date:  2012-10       Impact factor: 3.507

  6 in total

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