Mathieu Cabannes1, Antoine Bouissou2, Géraldine Favrais2, Catherine Sembély-Taveau1, Luciano Morales1, Amélie Favreau2, Philippe Bertrand3,4, Elie Saliba2,4, Dominique Sirinelli1,4, Baptiste Morel5,6. 1. Department of Pediatric Radiology, Clocheville Hospital, CHRU, 49 Boulevard Beranger, Tours, France. 2. Department of Neonatology, Clocheville Hospital, CHRU, 49 Boulevard Beranger, Tours, France. 3. Department of Radiology, Bretonneau Hospital, CHRU, 10 Boulevard Tonnellé, Tours, France. 4. Francois Rabelais University, Faculty of Medicine, Tours, France. 5. Department of Pediatric Radiology, Clocheville Hospital, CHRU, 49 Boulevard Beranger, Tours, France. baptiste.morel@univ-tours.fr. 6. Francois Rabelais University, Faculty of Medicine, Tours, France. baptiste.morel@univ-tours.fr.
Abstract
OBJECTIVE: The aim of the study was to better describe incidence, risk factors, and the natural evolution of neonatal portal vein thrombosis (PVT). STUDY DESIGN: One hundred and twenty-three premature newborns or with birth weight <1.5 kg were prospectively included in a single center during a one-year period. Three systematic abdominal ultrasound examinations at day 3, day 10, and day 45 (and 1 year in case of persistent PVT) were performed. Clinical and biological data were recorded. RESULTS: Seventy neonates (57%) had three normal US examinations. Fifty-three neonates (43%) had a clinical and biological asymptomatic left PVT. No right or extrahepatic portal venous thrombosis was observed. Umbilical vascular catheter (UVC) was removed in case of PVT. No anticoagulation therapy was required. No risk factor was significantly associated with PVT. At 1 year of follow-up, five infants had persistent isolated left PVT (4%). CONCLUSION: A spontaneous favorable evolution of left PVT occurred in more than of 95%.
OBJECTIVE: The aim of the study was to better describe incidence, risk factors, and the natural evolution of neonatal portal vein thrombosis (PVT). STUDY DESIGN: One hundred and twenty-three premature newborns or with birth weight <1.5 kg were prospectively included in a single center during a one-year period. Three systematic abdominal ultrasound examinations at day 3, day 10, and day 45 (and 1 year in case of persistent PVT) were performed. Clinical and biological data were recorded. RESULTS: Seventy neonates (57%) had three normal US examinations. Fifty-three neonates (43%) had a clinical and biological asymptomatic left PVT. No right or extrahepatic portal venous thrombosis was observed. Umbilical vascular catheter (UVC) was removed in case of PVT. No anticoagulation therapy was required. No risk factor was significantly associated with PVT. At 1 year of follow-up, five infants had persistent isolated left PVT (4%). CONCLUSION: A spontaneous favorable evolution of left PVT occurred in more than of 95%.