Amit Joshi1, Amitesh Anand2, Kumar Prabhash1, Vanita Noronha1, Sameer Shrirangwar1, Ganesh Bakshi2, Mahendra Pal2, Vedang Murthy3, Rahul Krishnatry3, Sangeeta Desai4, Santosh Menon4, Deepali Patil5, Sheetal Kulkarni6, Nilesh Sable7, Palak Popat7, Archi Agrawal8, Venkatesh Rangarajan8, Gagan Prakash2. 1. Department of Medical Oncology, Tata Memorial Hospital, Mumbai, Maharashtra, India. 2. Department of Surgical Oncology, Tata Memorial Hospital, Mumbai, Maharashtra, India. 3. Department of Radiation Oncology, Tata Memorial Hospital, Mumbai, Maharashtra, India. 4. Department of Pathology, Tata Memorial Hospital, Mumbai, Maharashtra, India. 5. Department of Clinical Pharmacology, Advanced Centre for Treatment, Research and Education in Cancer, Homi Bhabha National Institute, Mumbai, Maharashtra, India. 6. Department of Clinical Research Secretariat, Tata Memorial Hospital, Mumbai, Maharashtra, India. 7. Department of Radiodiagnosis, Tata Memorial Hospital, Mumbai, Maharashtra, India. 8. Department of Nuclear Medicine, Tata Memorial Hospital, Mumbai, Maharashtra, India.
Abstract
INTRODUCTION: The stage at diagnosis of renal cell cancer (RCC) in developed countries is lower due to increased utilization of routine health checkups by patients compared to developed countries. This study aims to determine the sociodemographic and clinical distribution of RCC in patients presenting to Tata Memorial Hospital (TMH). SUBJECTS AND METHODS: We performed a retrospective audit of all patients presenting to TMH with a diagnosis of RCC. Data were retrieved from our electronic medical record system from January 1, 2013 to December 31, 2013. The survival analysis was done by Kaplan-Meir analysis method of estimating survival. Log-rank test of comparison was applied to estimate the difference in the survival among the different stages of renal cancer. RESULTS: Of the 35,197 new registered patients at TMH, 338 were diagnosed with RCC. Most patients were in the 50-60 years age group, with 56.6 years being the median age at presentation. Among patients treated at TMH, 84 underwent surgery and tyrosine kinase inhibitor was given in 55 (16%) patients. The patients' characteristics, clinical characteristics of RCC, treatment modalities offered, and survival of patients treated for RCC are presented in this paper. CONCLUSION: In the absence of robust Indian data on RCC, this audit provides baseline information on epidemiology, stage at presentation, and outcomes of RCC at our center compared with the West.
INTRODUCTION: The stage at diagnosis of renal cell cancer (RCC) in developed countries is lower due to increased utilization of routine health checkups by patients compared to developed countries. This study aims to determine the sociodemographic and clinical distribution of RCC in patients presenting to Tata Memorial Hospital (TMH). SUBJECTS AND METHODS: We performed a retrospective audit of all patients presenting to TMH with a diagnosis of RCC. Data were retrieved from our electronic medical record system from January 1, 2013 to December 31, 2013. The survival analysis was done by Kaplan-Meir analysis method of estimating survival. Log-rank test of comparison was applied to estimate the difference in the survival among the different stages of renal cancer. RESULTS: Of the 35,197 new registered patients at TMH, 338 were diagnosed with RCC. Most patients were in the 50-60 years age group, with 56.6 years being the median age at presentation. Among patients treated at TMH, 84 underwent surgery and tyrosine kinase inhibitor was given in 55 (16%) patients. The patients' characteristics, clinical characteristics of RCC, treatment modalities offered, and survival of patients treated for RCC are presented in this paper. CONCLUSION: In the absence of robust Indian data on RCC, this audit provides baseline information on epidemiology, stage at presentation, and outcomes of RCC at our center compared with the West.
Entities:
Keywords:
Indian data; Tata Memorial Hospital; kidney cancer; renal cell carcinoma