Literature DB >> 30081105

Soluble B7-H3 (sB7-H3) is over-expressed in the serum of type 1 diabetes patients.

Chen Fang1, Sicheng Li2, Rongqin Xu3, Heming Guo2, Rong Jiang2, Sisi Ding4, Xiaohong Chen2, Yun Huang2, Ji Hu2, Cuiping Liu5, Yifeng Tu6.   

Abstract

Type 1 Diabetes (T1D) is an autoimmune disease resulting from insulin-secreting β-cells mediated by autoreactive T cells. We demonstrated increased level of sB7-H3 in T1D patients than in healthy control group. This result suggests that B7-H3 may be may be a promising biomarker associated with the pathogenesis of T1D.
Copyright © 2018 Elsevier B.V. All rights reserved.

Entities:  

Keywords:  B7-H3/CD276; Immune checkpoint; Soluble B7-H3; Type 1 diabetes

Mesh：

Substances：

Year:  2018        PMID： 30081105     DOI： 10.1016/j.diabres.2018.08.004

Source DB:  PubMed          Journal:  Diabetes Res Clin Pract        ISSN： 0168-8227            Impact factor:   5.602


  4 in total

1.  Clinical and Prognostic Relevance of B7-H3 and Indicators of Glucose Metabolism in Colorectal Cancer.

Authors:  Ting Zhang; Yufen Jin; Xin Jiang; Longhai Li; Xiaowei Qi; Yong Mao; Dong Hua
Journal:  Front Oncol       Date:  2020-09-15       Impact factor: 6.244

2.  B7-H3 participates in human salivary gland epithelial cells apoptosis through NF-κB pathway in primary Sjögren's syndrome.

Authors:  Ping Li; Ying Yang; Yi Jin; Rui Zhao; Chen Dong; Wenjie Zheng; Tianyi Zhang; Jing Li; Zhifeng Gu
Journal:  J Transl Med       Date:  2019-08-14       Impact factor: 5.531

3.  Soluble B7H3 level in breast cancer and its relationship with clinicopathological variables and T cell infiltration.

Authors:  Okan Avci; Eyyup Çavdar; Yakup İriağaç; Kubilay Karaboyun; Aliye Çelikkol; Tuğba İlkem Kurtoğlu Özçağlayan; Meltem Öznur; Sibel Özkan Gürdal; Erdoğan Selçuk Şeber
Journal:  Contemp Oncol (Pozn)       Date:  2022-02-11

4.  Evaluation of the role of B7-H3 haplotype in association with impaired B7-H3 expression and protection against type 1 diabetes in Chinese Han population.

Authors:  Sisi Ding; Yimei Shan; Lili Sun; Sicheng Li; Rong Jiang; Xin Chang; Ziyi Huang; Jing Sun; Cuiping Liu; Chen Fang; Xueguang Zhang
Journal:  BMC Endocr Disord       Date:  2020-08-12       Impact factor: 2.763
  4 in total

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