Literature DB >> 3008045

Giant multivesicular bodies in the rat hippocampal pyramidal cells after chronic alcohol consumption.

M M Paula-Barbosa, M M Borges, A Cadete-Leite, M A Tavares.   

Abstract

Multivesicular bodies (MVBs) with diameters up to 4.5 microns were observed in the hippocampal pyramidal cells of rats submitted to chronic alcohol consumption. A significant increase in the volumetric density (Vv) of these organelles was found in CA1 pyramidal cells. Transitional forms of MVBs towards lysosomes were seen. A failure in MVB's enzymatic hydrolytic mechanisms, due to the prolonged alcohol aggression, could underlie its formation.

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Year:  1986        PMID： 3008045     DOI： 10.1016/0304-3940(86)90353-8

Source DB:  PubMed          Journal:  Neurosci Lett        ISSN： 0304-3940            Impact factor:   3.046


  4 in total

Review 1.  Multivesicular bodies in neurons: distribution, protein content, and trafficking functions.

Authors:  Christopher S Von Bartheld; Amy L Altick
Journal:  Prog Neurobiol       Date:  2011-01-07       Impact factor: 11.685

2.  Can megadoses of thiamine prevent ethanol-induced damages of rat hippocampal CA1 pyramidal neurones?

Authors:  S Wenisch; T Steinmetz; B Fortmann; R Leiser; I Bitsch
Journal:  Z Ernahrungswiss       Date:  1996-09

3.  Chronic alcohol consumption and withdrawal do not induce cell death in the suprachiasmatic nucleus, but lead to irreversible depression of peptide immunoreactivity and mRNA levels.

Authors:  M D Madeira; J P Andrade; A R Lieberman; N Sousa; O F Almeida; M M Paula-Barbosa
Journal:  J Neurosci       Date:  1997-02-15       Impact factor: 6.167

Review 4.  Advances and New Concepts in Alcohol-Induced Organelle Stress, Unfolded Protein Responses and Organ Damage.

Authors:  Cheng Ji
Journal:  Biomolecules       Date:  2015-06-03
  4 in total

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