Literature DB >> 30079984

Asymmetric "Acetylenic" [3+2] Cycloaddition of Nitrones Catalyzed by Cationic Chiral PdII Lewis Acid.

Kazuya Honda1, Koichi Mikami1.   

Abstract

Highly enantioselective [3+2] cycloaddition of ynones and nitrones has been developed. Very bulky ligand, DTBM-SEGPHOS, was used for an effective asymmetric induction over distal reaction centers on the linear ynone dipolarophile and for prevention of PdII catalyst deactivation by coordination of the nitrones. The reaction has wide scope of substrates in both ynones and nitrones.
© 2018 Wiley-VCH Verlag GmbH & Co. KGaA, Weinheim.

Entities:  

Keywords:  alkynes; computational chemistry; cycloaddition; palladium; synthetic methods

Year:  2018        PMID： 30079984     DOI： 10.1002/asia.201801016

Source DB:  PubMed          Journal:  Chem Asian J        ISSN： 1861-471X


  3 in total

1.  Synthesis, Neuroprotection, and Antioxidant Activity of 1,1'-Biphenylnitrones as α-Phenyl-N-tert-butylnitrone Analogues in In Vitro Ischemia Models.

Authors:  Beatriz Chamorro; David García-Vieira; Daniel Diez-Iriepa; Estíbaliz Garagarza; Mourad Chioua; Dimitra Hadjipavlou-Litina; Francisco López-Muñoz; José Marco-Contelles; María Jesús Oset-Gasque
Journal:  Molecules       Date:  2021-02-20       Impact factor: 4.411

Review 2.  Further developments of β,γ-unsaturated α-ketoesters as versatile synthons in asymmetric catalysis.

Authors:  Ruixian Deng; Tian-Jiao Han; Xiang Gao; Yuan-Fu Yang; Guang-Jian Mei
Journal:  iScience       Date:  2022-02-11

3.  Fast MacMillan's Imidazolidinone-Catalyzed Enantioselective Synthesis of Polyfunctionalized 4-Isoxazoline Scaffolds.

Authors:  Dario Corbisiero; Tommaso Fantoni; Lucia Ferrazzano; Giulia Martelli; Paolo Cantelmi; Alexia Mattellone; Chiara Palladino; Magda Monari; Riccardo Pedrazzani; Alessandra Tolomelli; Walter Cabri
Journal:  ACS Omega       Date:  2022-07-20
  3 in total

北京卡尤迪生物科技股份有限公司 © 2022-2023.