Literature DB >> 30078095

Brief Report: Odour Awareness in Young Children with Autism Spectrum Disorders.

Hirokazu Kumazaki1, Masako Okamoto2, Yuko Yoshimura3, Takashi Ikeda3, Chiaki Hasegawa3, Daisuke N Saito3, Ryoichiro Iwanaga4, Sara Tomiyama3, Kyung-Min An3, Yoshio Minabe3, Mitsuru Kikuchi3.   

Abstract

The elucidation of odour awareness in children with autism spectrum disorders (ASD) is important. We compared the odour awareness of young children with ASD with those of typical development (TD) children using the Children's Olfactory Behavior in Everyday Life (COBEL) questionnaire, which is a self-report measure that mainly assesses odour awareness. Forty-five young boys (aged 5-6 years), including 20 children with ASD and 25 TD children, participated in this study. The total COBEL score of the young children with ASD was lower than that of the TD children (p < 0.01). Moreover, the total COBEL score was significantly correlated with the total VABS II score (p < 0.05). Our results improve understanding of the odour awareness in children with ASD.

Entities:  

Keywords:  Autism spectrum disorders; Odour awareness; Olfactory; Self-report; VABS II

Year:  2020        PMID: 30078095     DOI: 10.1007/s10803-018-3710-y

Source DB:  PubMed          Journal:  J Autism Dev Disord        ISSN: 0162-3257


  4 in total

1.  Effects of a postnatal Atrx conditional knockout in neurons on autism-like behaviours in male and female mice.

Authors:  Nicole Martin-Kenny; Nathalie G Bérubé
Journal:  J Neurodev Disord       Date:  2020-06-24       Impact factor: 4.025

2.  Haploinsufficiency of autism causative gene Tbr1 impairs olfactory discrimination and neuronal activation of the olfactory system in mice.

Authors:  Tzyy-Nan Huang; Tzu-Li Yen; Lily R Qiu; Hsiu-Chun Chuang; Jason P Lerch; Yi-Ping Hsueh
Journal:  Mol Autism       Date:  2019-02-11       Impact factor: 7.509

3.  Social behaviors and contextual memory of Vcp mutant mice are sensitive to nutrition and can be ameliorated by amino acid supplementation.

Authors:  Tzyy-Nan Huang; Yu-Tzu Shih; Si-Cih Lin; Yi-Ping Hsueh
Journal:  iScience       Date:  2020-12-15

4.  Exposure to GABAA Receptor Antagonist Picrotoxin in Pregnant Mice Causes Autism-Like Behaviors and Aberrant Gene Expression in Offspring.

Authors:  Hiroko Kotajima-Murakami; Hideo Hagihara; Atsushi Sato; Yoko Hagino; Miho Tanaka; Yoshihisa Katoh; Yasumasa Nishito; Yukio Takamatsu; Shigeo Uchino; Tsuyoshi Miyakawa; Kazutaka Ikeda
Journal:  Front Psychiatry       Date:  2022-02-03       Impact factor: 4.157

  4 in total

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