Literature DB >> 30077128

Functional assessment and satisfaction of transfemoral amputees with low mobility (FASTK2): A clinical trial of microprocessor-controlled vs. non-microprocessor-controlled knees.

Kenton R Kaufman1, Kathie A Bernhardt2, Kevin Symms3.   

Abstract

BACKGROUND: The benefits of a microprocessor-controlled knee are well documented in transfemoral amputees who are unlimited community ambulators. There have been suggestions that transfemoral amputees with limited community ambulation will also benefit from a microprocessor-controlled knee. Current medical policy restricts microprocessor-controlled knees to unlimited community ambulators and, thereby, potentially limits function. This clinical trial was performed to determine if limited community ambulators would benefit from a microprocessor-controlled knee.
METHODS: 50 unilateral transfemoral amputees, mean age 69, were tested using their current non-microprocessor-controlled knee, fit with a microprocessor-controlled knee and allowed 10 weeks of acclimation before being tested, and then retested with their original mechanical knee after 4 weeks of re-acclimation. Patient function was assessed in the free-living environment using tri-axial accelerometers. Patient satisfaction and safety were also measured.
FINDINGS: The subjects demonstrated improved outcomes when using the microprocessor-controlled knee. Subjects had a significant reduction in falls, spent less time sitting, and increased their activity level. Subjects also reported significantly better ambulation, improved appearance, and greater utility.
INTERPRETATION: This clinical trial demonstrated that transfemoral amputees with limited mobility clearly benefit from a microprocessor-controlled knee. Notably, a reduction in falls occurred while the subjects engaged in more physical activity, which resulted in increased subject satisfaction. The increased activity resulted in a greater exposure to fall risk, but that risk was moderated by the advanced technology. ClinicalTrials.gov No: NCT02240186.
Copyright © 2018 Elsevier Ltd. All rights reserved.

Entities:  

Keywords:  Amputees; Knee prosthesis; Locomotion; Microprocessor; Quality of life; Treatment outcome

Mesh:

Year:  2018        PMID: 30077128     DOI: 10.1016/j.clinbiomech.2018.07.012

Source DB:  PubMed          Journal:  Clin Biomech (Bristol, Avon)        ISSN: 0268-0033            Impact factor:   2.063


  10 in total

1.  Design of a Semi-Powered Stance-Control Swing-Assist Transfemoral Prosthesis.

Authors:  J T Lee; H L Bartlett; M Goldfarb
Journal:  IEEE ASME Trans Mechatron       Date:  2019-11-07       Impact factor: 5.303

2.  The Kenevo microprocessor-controlled prosthetic knee compared with non-microprocessor-controlled knees in individuals older than 65 years in Sweden: A cost-effectiveness and budget-impact analysis.

Authors:  Alexander Kuhlmann; Kerstin Hagberg; Ilka Kamrad; Nerrolyn Ramstrand; Susanne Seidinger; Hans Berg
Journal:  Prosthet Orthot Int       Date:  2022-05-03       Impact factor: 1.672

3.  OASIS 1: Retrospective analysis of four different microprocessor knee types.

Authors:  James H Campbell; Phillip M Stevens; Shane R Wurdeman
Journal:  J Rehabil Assist Technol Eng       Date:  2020-11-05

4.  Skeletal muscle mitochondrial dysfunction and muscle and whole body functional deficits in cancer patients with weight loss.

Authors:  Hawley E Kunz; John D Port; Kenton R Kaufman; Aminah Jatoi; Corey R Hart; Kevin J Gries; Ian R Lanza; Rajiv Kumar
Journal:  J Appl Physiol (1985)       Date:  2021-12-23

5.  Technology for monitoring everyday prosthesis use: a systematic review.

Authors:  Alix Chadwell; Laura Diment; M Micó-Amigo; Dafne Z Morgado Ramírez; Alex Dickinson; Malcolm Granat; Laurence Kenney; Sisary Kheng; Mohammad Sobuh; Robert Ssekitoleko; Peter Worsley
Journal:  J Neuroeng Rehabil       Date:  2020-07-14       Impact factor: 4.262

6.  Survey of transfemoral amputee experience and priorities for the user-centered design of powered robotic transfemoral prostheses.

Authors:  Chiara Fanciullacci; Zach McKinney; Angelo Davalli; Rinaldo Sacchetti; Simona Crea; Nicola Vitiello; Emanuele Gruppioni; Vito Monaco; Giovanni Milandri; Matteo Laffranchi; Lorenzo De Michieli; Andrea Baldoni; Alberto Mazzoni; Linda Paternò; Elisa Rosini; Luigi Reale; Fabio Trecate
Journal:  J Neuroeng Rehabil       Date:  2021-12-04       Impact factor: 4.262

7.  Characterizing the Gait of People With Different Types of Amputation and Prosthetic Components Through Multimodal Measurements: A Methodological Perspective.

Authors:  Cristiano De Marchis; Simone Ranaldi; Tiwana Varrecchia; Mariano Serrao; Stefano Filippo Castiglia; Antonella Tatarelli; Alberto Ranavolo; Francesco Draicchio; Francesco Lacquaniti; Silvia Conforto
Journal:  Front Rehabil Sci       Date:  2022-03-17

8.  Can microprocessor knees reduce the disparity in trips and falls risks between above and below knee prosthesis users?

Authors:  Michael McGrath; Laura A Gray; Beata Rek; Kate C Davies; Zoe Savage; Jane McLean; Alison Stenson; Saeed Zahedi
Journal:  PLoS One       Date:  2022-09-02       Impact factor: 3.752

9.  Cost-effectiveness and budget impact of the microprocessor-controlled knee C-Leg in transfemoral amputees with and without diabetes mellitus.

Authors:  Alexander Kuhlmann; Henning Krüger; Susanne Seidinger; Andreas Hahn
Journal:  Eur J Health Econ       Date:  2020-01-02

Review 10.  Reported Outcome Measures in Studies of Real-World Ambulation in People with a Lower Limb Amputation: A Scoping Review.

Authors:  Mirjam Mellema; Terje Gjøvaag
Journal:  Sensors (Basel)       Date:  2022-03-14       Impact factor: 3.576

  10 in total

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