Literature DB >> 30076278

Non-Small Cell Lung Cancer in Countries of Central and Southeastern Europe: Diagnostic Procedures and Treatment Reimbursement Surveyed by the Central European Cooperative Oncology Group.

Ales Ryska1, Rares Buiga2, Albena Fakirova3, Izidor Kern4, Włodzimierz Olszewski5, Lukas Plank6, Sven Seiwerth7, Erika Toth8, Eri Zivka9, Christiane Thallinger10,11, Christoph Zielinski12,11, Luka Brcic13.   

Abstract

This article analyzes the availability of different diagnostic procedures of non-small cell lung cancer (NSCLC) and the reimbursement landscape of drugs for NSCLC in countries of central and southeastern Europe (CEE). A survey was conducted by the Central European Cooperative Oncology Group. Results of the survey show that both availability and reimbursement of diagnoses of molecular alterations in NSCLC, the detection of which is essential for therapeutic decisions, varies widely between countries of CEE. Not only is "reflex" testing often substituted by analyses performed only "on demand," but reimbursement of such assessments varies widely between unavailability and payments by the health care system or even pharmaceutical companies. It was concluded that a structured access to testing and reimbursement should be the aim in order to provide patients with appropriate therapeutic options. IMPLICATIONS FOR PRACTICE: This article provides an overview of the limitations in lung cancer treatment in countries of central and southeastern Europe, as well as the reimbursement status of various lung cancer treatment regimens in these countries, which directly impacts treatment options. © AlphaMed Press 2018.

Entities:  

Keywords:  Central and Southeastern Europe; Molecular alterations; Non‐small cell lung cancer; Precision medicine; Reimbursement

Mesh:

Year:  2018        PMID: 30076278      PMCID: PMC6292534          DOI: 10.1634/theoncologist.2018-0008

Source DB:  PubMed          Journal:  Oncologist        ISSN: 1083-7159


  12 in total

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Authors:  Natasha Rekhtman; Natasha B Leighl; Mark R Somerfield
Journal:  J Oncol Pract       Date:  2014-12-16       Impact factor: 3.840

2.  Cancer Control in Central and Eastern Europe: Current Situation and Recommendations for Improvement.

Authors:  Eduard Vrdoljak; Gyorgy Bodoky; Jacek Jassem; Razvan A Popescu; Jozef Mardiak; Robert Pirker; Tanja Čufer; Semir Bešlija; Alexandru Eniu; Vladimir Todorović; Kateřina Kubáčková; Galia Kurteva; Zorica Tomašević; Agim Sallaku; Snezhana Smichkoska; Žarko Bajić; Branimir I Šikić
Journal:  Oncologist       Date:  2016-07-08

3.  Using multiplexed assays of oncogenic drivers in lung cancers to select targeted drugs.

Authors:  Mark G Kris; Bruce E Johnson; Lynne D Berry; David J Kwiatkowski; A John Iafrate; Ignacio I Wistuba; Marileila Varella-Garcia; Wilbur A Franklin; Samuel L Aronson; Pei-Fang Su; Yu Shyr; D Ross Camidge; Lecia V Sequist; Bonnie S Glisson; Fadlo R Khuri; Edward B Garon; William Pao; Charles Rudin; Joan Schiller; Eric B Haura; Mark Socinski; Keisuke Shirai; Heidi Chen; Giuseppe Giaccone; Marc Ladanyi; Kelly Kugler; John D Minna; Paul A Bunn
Journal:  JAMA       Date:  2014-05-21       Impact factor: 56.272

4.  Metastatic non-small-cell lung cancer (NSCLC): ESMO Clinical Practice Guidelines for diagnosis, treatment and follow-up.

Authors:  M Reck; S Popat; N Reinmuth; D De Ruysscher; K M Kerr; S Peters
Journal:  Ann Oncol       Date:  2014-08-11       Impact factor: 32.976

5.  Metastatic non-small-cell lung cancer: ESMO Clinical Practice Guidelines for diagnosis, treatment and follow-up.

Authors:  S Novello; F Barlesi; R Califano; T Cufer; S Ekman; M Giaj Levra; K Kerr; S Popat; M Reck; S Senan; G V Simo; J Vansteenkiste; S Peters
Journal:  Ann Oncol       Date:  2016-09       Impact factor: 32.976

Review 6.  Management of advanced non-small cell lung cancers with known mutations or rearrangements: latest evidence and treatment approaches.

Authors:  Meghan Shea; Daniel B Costa; Deepa Rangachari
Journal:  Ther Adv Respir Dis       Date:  2015-11-30       Impact factor: 4.031

7.  ESMO International Consortium Study on the availability, out-of-pocket costs and accessibility of antineoplastic medicines in countries outside of Europe.

Authors:  N I Cherny; R Sullivan; J Torode; M Saar; A Eniu
Journal:  Ann Oncol       Date:  2017-11-01       Impact factor: 32.976

8.  Activating mutations in the epidermal growth factor receptor underlying responsiveness of non-small-cell lung cancer to gefitinib.

Authors:  Thomas J Lynch; Daphne W Bell; Raffaella Sordella; Sarada Gurubhagavatula; Ross A Okimoto; Brian W Brannigan; Patricia L Harris; Sara M Haserlat; Jeffrey G Supko; Frank G Haluska; David N Louis; David C Christiani; Jeff Settleman; Daniel A Haber
Journal:  N Engl J Med       Date:  2004-04-29       Impact factor: 91.245

9.  ESMO European Consortium Study on the availability, out-of-pocket costs and accessibility of antineoplastic medicines in Europe.

Authors:  N Cherny; R Sullivan; J Torode; M Saar; A Eniu
Journal:  Ann Oncol       Date:  2016-08       Impact factor: 32.976

10.  NSCLC molecular testing in Central and Eastern European countries.

Authors:  Ales Ryska; Peter Berzinec; Luka Brcic; Tanja Cufer; Rafal Dziadziuszko; Maya Gottfried; Ilona Kovalszky; Włodzimierz Olszewski; Buge Oz; Lukas Plank; Jozsef Timar
Journal:  BMC Cancer       Date:  2018-03-09       Impact factor: 4.430

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  6 in total

1.  Financing and Reimbursement Models for Personalised Medicine: A Systematic Review to Identify Current Models and Future Options.

Authors:  Rositsa Koleva-Kolarova; James Buchanan; Heleen Vellekoop; Simone Huygens; Matthijs Versteegh; Maureen Rutten-van Mölken; László Szilberhorn; Tamás Zelei; Balázs Nagy; Sarah Wordsworth; Apostolos Tsiachristas
Journal:  Appl Health Econ Health Policy       Date:  2022-04-04       Impact factor: 3.686

Review 2.  Lung cancer biomarker testing: perspective from Europe.

Authors:  Erik Thunnissen; Birgit Weynand; Dalma Udovicic-Gagula; Luka Brcic; Malgorzata Szolkowska; Paul Hofman; Silvana Smojver-Ježek; Sisko Anttila; Fiorella Calabrese; Izidor Kern; Birgit Skov; Sven Perner; Vibeke G Dale; Zivka Eri; Alex Haragan; Diana Leonte; Lina Carvallo; Spasenja Savic Prince; Siobhan Nicholson; Irene Sansano; Ales Ryska
Journal:  Transl Lung Cancer Res       Date:  2020-06

3.  Access to Novel Drugs for Non-Small Cell Lung Cancer in Central and Southeastern Europe: A Central European Cooperative Oncology Group Analysis.

Authors:  Tanja Cufer; Tudor E Ciuleanu; Peter Berzinec; Gabriela Galffy; Marko Jakopovic; Jacek Jassem; Dragana Jovanovic; Zhasmina Mihaylova; Gyula Ostoros; Christiane Thallinger; Milada Zemanova; Christoph Zielinski
Journal:  Oncologist       Date:  2019-11-29

4.  Treatment patterns, testing practices, and outcomes in the pre-FLAURA era for patients with EGFR mutation-positive advanced NSCLC: a retrospective chart review (REFLECT).

Authors:  Alfredo Addeo; Maximilian Hochmair; Urska Janzic; Elizabeth Dudnik; Andriani Charpidou; Adam Płużański; Tudor Ciuleanu; Ivan Shterev Donev; Judith Elbaz; Jørgen Aarøe; René Ott; Nir Peled
Journal:  Ther Adv Med Oncol       Date:  2021-11-29       Impact factor: 8.168

5.  Real-World Testing Practices, Treatment Patterns and Clinical Outcomes in Patients from Central Eastern Europe with EGFR-Mutated Advanced Non-Small Cell Lung Cancer: A Retrospective Chart Review Study (REFLECT).

Authors:  Urška Janžič; Nina Turnšek; Mircea Dediu; Ivan Shterev Donev; Roxana Lupu; Gabriela Teodorescu; Tudor E Ciuleanu; Adam Pluzanski
Journal:  Curr Oncol       Date:  2022-08-17       Impact factor: 3.109

6.  Immunotherapy for Metastatic Non-Small Cell Lung Cancer: Real-World Data from an Academic Central and Eastern European Center.

Authors:  Marija Ivanović; Lea Knez; Ana Herzog; Mile Kovačević; Tanja Cufer
Journal:  Oncologist       Date:  2021-08-02
  6 in total

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