| Literature DB >> 30075127 |
Elizabeth L Siegler1, Yanni Zhu2, Pin Wang3, Lili Yang4.
Abstract
CAR-T therapy has shown great success treating blood cancers, but drawbacks include high manufacturing costs and potentially fatal toxicities such as cytokine release syndrome. In this issue of Cell Stem Cell, Li et al. (2018) describe how engineered iPSC-derived NK cells armed with NK-tailored CAR constructs (CAR-iPSC-NK cells) provide better options for anti-cancer immunotherapy.Entities:
Mesh:
Substances:
Year: 2018 PMID: 30075127 DOI: 10.1016/j.stem.2018.07.007
Source DB: PubMed Journal: Cell Stem Cell ISSN: 1875-9777 Impact factor: 24.633