Literature DB >> 30073868

Oral Antibiotics Are Effective for the Treatment of Hand Osteomyelitis in Children.

Jennifer S Kargel1, Douglas M Sammer1, Ronnie A Pezeshk1, Jonathan Cheng1.   

Abstract

Background: Acute osteomyelitis of the hand is common in the pediatric population. Treatment with intravenous antibiotics is expensive and is associated with catheter-site infection and thrombosis. The purpose of this study is to investigate the efficacy of managing osteomyelitis of the hand in children with oral antibiotics.
Methods: A retrospective review of cases of acute osteomyelitis of the hand at a single pediatric institution over a 4.5-year period was performed. Demographic and clinical data were reviewed, and treatment courses and outcomes were analyzed.
Results: In total, 21 patients with acute osteomyelitis of the hand were included in the study. Of the 21 patients, 17 were initiated on a 6-week course of oral antibiotics upon diagnosis. Thirteen were successfully treated with oral antibiotics alone, 3 required subsequent surgical debridement, and 3 required conversion to intravenous antibiotics. Of the 21 patients, 4 were treated with surgical debridement upon diagnosis due to gross purulent drainage and then initiated on a 6-week course of oral antibiotics. All patients who underwent debridement were treated successfully with postoperative oral antibiotics. Conclusions: Most cases of osteomyelitis of the hand in children can be treated with oral antibiotics, either as the primary treatment or as postoperative therapy. Surgical debridement is indicated when purulence is present at the time of initial diagnosis or if the infection progresses during treatment with oral antibiotics. The use of oral antibiotics for treating acute osteomyelitis of the hand in children may result in decreased cost and fewer catheter-associated complications.

Entities:  

Keywords:  antibiotics; hand; infection; osteomyelitis; pediatric

Mesh:

Substances:

Year:  2018        PMID: 30073868      PMCID: PMC7076610          DOI: 10.1177/1558944718788666

Source DB:  PubMed          Journal:  Hand (N Y)        ISSN: 1558-9447


  9 in total

Review 1.  Treating osteomyelitis: antibiotics and surgery.

Authors:  Nalini Rao; Bruce H Ziran; Benjamin A Lipsky
Journal:  Plast Reconstr Surg       Date:  2011-01       Impact factor: 4.730

Review 2.  Antibiotic treatment of osteomyelitis: what have we learned from 30 years of clinical trials?

Authors:  Luca Lazzarini; Benjamin A Lipsky; Jon T Mader
Journal:  Int J Infect Dis       Date:  2005-05       Impact factor: 3.623

3.  Complications of central venous catheters used for the treatment of acute hematogenous osteomyelitis.

Authors:  Rebecca Ruebner; Ron Keren; Susan Coffin; Jaclyn Chu; David Horn; Theoklis E Zaoutis
Journal:  Pediatrics       Date:  2006-04       Impact factor: 7.124

4.  Retrospective assessment of subacute or chronic osteomyelitis in children and young adults.

Authors:  Jane S Auh; Helen J Binns; Ben Z Katz
Journal:  Clin Pediatr (Phila)       Date:  2004 Jul-Aug       Impact factor: 1.168

5.  Changing trends in acute osteomyelitis in children: impact of methicillin-resistant Staphylococcus aureus infections.

Authors:  Jesús Saavedra-Lozano; Asunción Mejías; Naveed Ahmad; Estrella Peromingo; Monica I Ardura; Sara Guillen; Ali Syed; Dominick Cavuoti; Octavio Ramilo
Journal:  J Pediatr Orthop       Date:  2008 Jul-Aug       Impact factor: 2.324

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Journal:  Pediatrics       Date:  1980-05       Impact factor: 7.124

7.  Oral antibiotic therapy for skeletal infections of children. I. Antibiotic concentrations in suppurative synovial fluid.

Authors:  J D Nelson; J B Howard; S Shelton
Journal:  J Pediatr       Date:  1978-01       Impact factor: 4.406

Review 8.  Role of oral antimicrobial therapy in the management of osteomyelitis.

Authors:  Jennifer A Shuford; James M Steckelberg
Journal:  Curr Opin Infect Dis       Date:  2003-12       Impact factor: 4.915

9.  Oral antibiotic therapy for skeletal infections of children. II. Therapy of osteomyelitis and suppurative arthritis.

Authors:  T R Tetzlaff; G H McCracken; J D Nelson
Journal:  J Pediatr       Date:  1978-03       Impact factor: 4.406

  9 in total
  2 in total

1.  Delayed Presentation of Seymour Fractures: A Single Institution Experience and Management Recommendations.

Authors:  Richard Samade; James S Lin; James E Popp; Julie Balch Samora
Journal:  Hand (N Y)       Date:  2019-10-09

2.  Oral Antibiotic Management of Acute Osteomyelitis of the Hand: Outcomes and Cost Comparison to Standard Intravenous Regimen.

Authors:  Mark Henry; Forrest H Lundy
Journal:  Hand (N Y)       Date:  2019-09-06
  2 in total

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