M Anne Harris1,2,3, Tracy L Kirkham2, Jill S MacLeod3, Michael Tjepkema4, Paul A Peters5, Paul A Demers2,3. 1. School of Occupational and Public Health, Ryerson University, Toronto, Ontario, Canada. 2. Dalla Lana School of Public Health, University of Toronto, Toronto, Ontario, Canada. 3. Occupational Cancer Research Centre, Cancer Care Ontario, Toronto, Ontario, Canada. 4. Statistics Canada, Health Analysis Division, Toronto, Ontario, Canada. 5. Department of Health Sciences, Carleton University, Toronto, Ontario, Canada.
Abstract
BACKGROUND: Firefighters, police, and armed services may be exposed to hazards such as combustion by-products and shift work. METHODS: The CanCHEC cohort linked 1991 census data to the Canadian cancer registry for follow up. Cox proportional hazards modeling was used to estimate hazard ratios (HRs) and 95% confidence intervals (CIs) to estimate risks for firefighter, police, or armed forces compared to workers in other occupations. RESULTS: The cohort of 1 108 410 men included 4535 firefighters, 10 055 police, and 9165 armed forces. For firefighters, elevated risks were noted for Hodgkin's lymphoma (HR: 2.89, 95%CI: 1.29-6.46), melanoma (HR: 1.67, 95%CI: 1.17-2.37), and prostate cancer (HR: 1.18, 95%CI: 1.01-1.37). Police had elevated risks for melanoma (HR:1.69, 95%CI: 1.32-2.16) and prostate cancer (HR:1.28, 95%CI: 1.14-1.42). No significant associations were found for armed forces workers. CONCLUSIONS: Canadian firefighters, police, and armed services, may be at an increased risk of developing certain cancers. Results suggested that a healthy worker effect may influence risk estimates.
BACKGROUND: Firefighters, police, and armed services may be exposed to hazards such as combustion by-products and shift work. METHODS: The CanCHEC cohort linked 1991 census data to the Canadian cancer registry for follow up. Cox proportional hazards modeling was used to estimate hazard ratios (HRs) and 95% confidence intervals (CIs) to estimate risks for firefighter, police, or armed forces compared to workers in other occupations. RESULTS: The cohort of 1 108 410 men included 4535 firefighters, 10 055 police, and 9165 armed forces. For firefighters, elevated risks were noted for Hodgkin's lymphoma (HR: 2.89, 95%CI: 1.29-6.46), melanoma (HR: 1.67, 95%CI: 1.17-2.37), and prostate cancer (HR: 1.18, 95%CI: 1.01-1.37). Police had elevated risks for melanoma (HR:1.69, 95%CI: 1.32-2.16) and prostate cancer (HR:1.28, 95%CI: 1.14-1.42). No significant associations were found for armed forces workers. CONCLUSIONS: Canadian firefighters, police, and armed services, may be at an increased risk of developing certain cancers. Results suggested that a healthy worker effect may influence risk estimates.
Authors: Mayris P Webber; Ankura Singh; Rachel Zeig-Owens; Joke Salako; Molly Skerker; Charles B Hall; David G Goldfarb; Nadia Jaber; Robert D Daniels; David J Prezant Journal: Occup Environ Med Date: 2021-09-10 Impact factor: 4.948
Authors: Paolo Boffetta; David G Goldfarb; Rachel Zeig-Owens; Dana Kristjansson; Jiehui Li; Robert M Brackbill; Mark R Farfel; James E Cone; Janette Yung; Amy R Kahn; Baozhen Qiao; Maria J Schymura; Mayris P Webber; David J Prezant; Christopher R Dasaro; Andrew C Todd; Charles B Hall Journal: JID Innov Date: 2021-10-13