Literature DB >> 30072564

Lesson of the month 2: Blunt abdominal trauma: atypical presentation of phaeochromocytoma.

Sarah Faloon1, Hema Venkataraman2, Kassiani Skordilis2, Ewen A Griffiths2, Neil Jl Gittoes2, Zaki K Hassan-Smith2,3, John Ayuk2.   

Abstract

A 26-year-old man presented following blunt abdominal trauma to a regional major trauma centre for emergency embolisation of a retroperitoneal bleed from a presumed renal laceration. Imaging had also revealed a large right suprarenal mass. Embolisation resulted in a hypertensive crisis raising the suspicion of a metabolically active adrenal tumour. The course was further complicated by the development of ischaemic bowel requiring emergency laparotomy. Intraoperatively he became haemodynamically unstable from an actively haemorrhaging lesion. Emergency laparotomy and adrenalectomy was performed as a life-saving procedure. Histology confirmed a phaeochromocytoma. The patient made a gradual recovery and was discharged home with no sequelae. Definitive management of phaeochromocytoma is surgical resection which requires prolonged preoperative optimisation with alpha receptor blockers to adequately control blood pressure and prevent hypertensive crises. Parenteral alpha receptor blockers, such as phentolamine, are optimal treatment for intraoperative hypertensive emergencies, yet they are currently not available in the UK. © Royal College of Physicians 2018. All rights reserved.

Entities:  

Keywords:  Phaeochromocytoma; abdominal trauma; ­interventional radiology

Mesh:

Year:  2018        PMID: 30072564      PMCID: PMC6334037          DOI: 10.7861/clinmedicine.18-4-345

Source DB:  PubMed          Journal:  Clin Med (Lond)        ISSN: 1470-2118            Impact factor:   2.659


  7 in total

1.  Embolisation of pheochromocytoma to stabilise and wean a patient in cardiogenic shock from emergency extracorporeal life support.

Authors:  Helle Vagner; Thomas Morris Hey; Bo Elle; Marianne Kjær Jensen
Journal:  BMJ Case Rep       Date:  2015-03-03

2.  Pheochromocytoma crisis is not a surgical emergency.

Authors:  Anouk Scholten; Robin M Cisco; Menno R Vriens; Jenny K Cohen; Elliot J Mitmaker; Chienying Liu; J Blake Tyrrell; Wen T Shen; Quan-Yang Duh
Journal:  J Clin Endocrinol Metab       Date:  2013-01-02       Impact factor: 5.958

3.  Pheochromocytoma and paraganglioma: an endocrine society clinical practice guideline.

Authors:  Jacques W M Lenders; Quan-Yang Duh; Graeme Eisenhofer; Anne-Paule Gimenez-Roqueplo; Stefan K G Grebe; Mohammad Hassan Murad; Mitsuhide Naruse; Karel Pacak; William F Young
Journal:  J Clin Endocrinol Metab       Date:  2014-06       Impact factor: 5.958

4.  A fatal complication caused by occult pheochromocytoma after splenic artery embolization for malignant hypersplenism.

Authors:  Wouter Dinkelaar; Otto Elgersma; Mark-David Levin
Journal:  Cardiovasc Intervent Radiol       Date:  2012-08       Impact factor: 2.740

5.  Spontaneous adrenal pheochromocytoma rupture complicated by intraperitoneal hemorrhage and shock.

Authors:  Joseph S Hanna; Philip J Spencer; Cornelia Savopoulou; Edward Kwasnik; Reza Askari
Journal:  World J Emerg Surg       Date:  2011-08-15       Impact factor: 5.469

6.  Implications and considerations during pheochromocytoma resection: A challenge to the anesthesiologist.

Authors:  Sukhminderjit Singh Bajwa; Sukhwinder Kaur Bajwa
Journal:  Indian J Endocrinol Metab       Date:  2011-10

7.  Anaesthetic management of a case of adrenal and extra-adrenal phaeochromocytoma for preoperative embolisation.

Authors:  Mathews Jacob; Saurabh Macwana; D Vivekanand
Journal:  Indian J Anaesth       Date:  2015-03
  7 in total
  3 in total

1.  Response.

Authors:  Zaki Hassan-Smith; Sarah Faloon; Neil Gittoes; John Ayuk
Journal:  Clin Med (Lond)       Date:  2019-01       Impact factor: 2.659

2.  Mechanical circulatory support such as extracorporeal membrane oxygenation is indicated in phaeochromocytoma crisis with sustained hypotension.

Authors:  Benjamin C Whitelaw; Julia K Prague; Omar G Mustafa
Journal:  Clin Med (Lond)       Date:  2019-01       Impact factor: 2.659

3.  Established endocrine practice.

Authors:  Sam M O'Toole; Morris J Brown; William M Drake
Journal:  Clin Med (Lond)       Date:  2019-01       Impact factor: 2.659

  3 in total

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