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Literature DB >> 3007098

Physiological aspects of free-radical reactions.

I Yamazaki, M Tamura, R Nakajima, M Nakamura.

Abstract

Enzymes which catalyze the formation of free radicals in vitro will catalyze similar reactions in vivo. We believe that the formation of some kinds of free radicals has definite physiological meanings in metabolism. In this sense, the enzymes forming such free radicals are concluded to be in evolutionally advanced states. Elaborated structure and function of enzymes such as horseradish peroxidase and microsomal flavoproteins support the idea. Deleterious and side reactions caused by free radicals are assumed to be minimized in vivo by localizing the reactions, but this assumption should be verified by future studies.

Entities: Chemical Species

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Year: 1985 PMID： 3007098 PMCID： PMC1568608 DOI： 10.1289/ehp.8564331

Source DB: PubMed Journal: Environ Health Perspect ISSN： 0091-6765 Impact factor: 9.031

124 in total

1. REDUCED NICOTINAMIDE-ADENINE DINUCLEOTIDE-DEPENDENT REDUCTION OF SEMIDEHYDROASCORBIC ACID.

Authors: W SCHNEIDER; H STAUDINGER
Journal: Biochim Biophys Acta Date: 1965-01

2. Ascorbic acid and photosynthesis. I. Monodehydroascorbic acid reductase of chloroplasts.

Authors: E MARRE; O ARRIGONI
Journal: Biochim Biophys Acta Date: 1958-12

3. Indoleamine 2,3-dioxygenase. Kinetic studies on the binding of superoxide anion and molecular oxygen to enzyme.

Authors: T Taniguchi; M Sono; F Hirata; O Hayaishi; M Tamura; K Hayashi; T Iizuka; Y Ishimura
Journal: J Biol Chem Date: 1979-05-10 Impact factor: 5.157

4. Tissue, subcellular, and submitochondrial distributions of semidehydroascorbate reductase: possible role of semidehydroascorbate reductase in cofactor regeneration.

Authors: E J Diliberto; G Dean; C Carter; P L Allen
Journal: J Neurochem Date: 1982-08 Impact factor: 5.372

5. Aniline is hydroxylated by the cytochrome P-450-dependent hydroxyl radical-mediated oxygenation mechanism.

Authors: M Ingelman-Sundberg; G Ekström
Journal: Biochem Biophys Res Commun Date: 1982-05-31 Impact factor: 3.575

6. Evidence for a homolytic mechanism of peroxide oxygen--oxygen bond cleavage during substrate hydroxylation by cytochrome P-450.

Authors: R E White; S G Sligar; M J Coon
Journal: J Biol Chem Date: 1980-12-10 Impact factor: 5.157

7. The involvement of cytochrome P-450 in hepatic microsomal steroid hydroxylation reactions supported by sodium periodate, sodium chlorite, and organic hydroperoxides.

Authors: E G Hrycay; J A Gustafsson; M Ingelman-Sundberg; L Ernster
Journal: Eur J Biochem Date: 1976-01-02

4. Evaluation of the Anti-Leishmania mexicana and -Trypanosoma brucei Activity and Mode of Action of 4,4'-(Arylmethylene)bis(3-methyl-1-phenyl-1H-pyrazol-5-ol).

Authors: Olalla Barreiro-Costa; Cristina Quiroga Lozano; Erika Muñoz; Patricio Rojas-Silva; Andrea Medeiros; Marcelo A Comini; Jorge Heredia-Moya
Journal: Biomedicines Date: 2022-08-07

4 in total

Physiological aspects of free-radical reactions.

1. REDUCED NICOTINAMIDE-ADENINE DINUCLEOTIDE-DEPENDENT REDUCTION OF SEMIDEHYDROASCORBIC ACID.

2. Ascorbic acid and photosynthesis. I. Monodehydroascorbic acid reductase of chloroplasts.

3. Indoleamine 2,3-dioxygenase. Kinetic studies on the binding of superoxide anion and molecular oxygen to enzyme.

4. Tissue, subcellular, and submitochondrial distributions of semidehydroascorbate reductase: possible role of semidehydroascorbate reductase in cofactor regeneration.

5. Aniline is hydroxylated by the cytochrome P-450-dependent hydroxyl radical-mediated oxygenation mechanism.

6. Evidence for a homolytic mechanism of peroxide oxygen--oxygen bond cleavage during substrate hydroxylation by cytochrome P-450.

7. The involvement of cytochrome P-450 in hepatic microsomal steroid hydroxylation reactions supported by sodium periodate, sodium chlorite, and organic hydroperoxides.

8. Redox properties of microsomal reduced nicotinamide adenine dinucleotide-cytochrome b5 reductase and cytochrome b5.

9. The reaction of superoxide radical with catalase. Mechanism of the inhibition of catalase by superoxide radical.

10. Characterization of the free radical of mammalian ribonucleotide reductase.

Review 1. Free radical mediated cell toxicity by redox cycling chemicals.

2. Influence of superoxide on myeloperoxidase kinetics measured with a hydrogen peroxide electrode.

3. Peroxidative metabolism of beta2-agonists salbutamol and fenoterol and their analogues.

4. Evaluation of the Anti-Leishmania mexicana and -Trypanosoma brucei Activity and Mode of Action of 4,4'-(Arylmethylene)bis(3-methyl-1-phenyl-1H-pyrazol-5-ol).