Literature DB >> 30069373

Diagnosis of the cause of chronic dyspnoea in primary and tertiary care: characterizing diagnostic confidence.

Yao C Huang1,2, Olivia R Ferry1,2, Scott C McKenzie2,3, Rayleen V Bowman1,2, Michael Hamilton4, Philip J Masel1,2, Kwun M Fong1,2, Ian A Yang1,2.   

Abstract

BACKGROUND: Chronic dyspnoea (breathlessness) in adults is a common symptom, the exact cause of which may be difficult to diagnose on initial presentation. We characterised the diagnostic complexity of chronic dyspnoea in primary care and tertiary care.
METHODS: This retrospective observational study screened consecutive referral letters of all adult patients referred to cardiology or respiratory clinics at a tertiary referral hospital, during May to June 2015. For patients referred due to chronic dyspnoea, data were analysed from the initial referral letter and subsequent specialist clinic letters for the 6-month time period after referral.
RESULTS: Of 1,370 patient referrals, 122 patients (mean age 63 y, 55% female) were referred due to chronic dyspnoea. One hundred and five patients (86%) were referred from primary care and 17 (14%) from other hospital clinics. Sixty-one percent were referred with an evident diagnosis (referrer was confident of the initial diagnosis), whereas 39% had non-evident or unclear diagnoses. By 6 months after referral, a definitive final diagnosis had been determined by the specialist clinics in 62% of patients. The majority of patients had been referred appropriately to a cardiology or respiratory clinic, based on the final diagnosis. However, only 26% of diagnoses were fully concordant between the initial referrer diagnosis and the final specialist clinic diagnosis, with 26% being partially concordant and 48% non-concordant. Diagnostic certainty of the referrer was associated with concordance of diagnosis between the referrer and specialist clinic (P<0.001).
CONCLUSIONS: In adult patients referred due to chronic dyspnoea to hospital specialist clinics, there is considerable diagnostic uncertainty about its aetiology, for both referring doctors and specialist clinics. These results demonstrate the current difficulty in diagnosing the cause of chronic dyspnoea in adults, and highlight the need for evidence-based diagnostic pathways.

Entities:  

Keywords:  Dyspnoea; concordance; diagnosis; uncertainty

Year:  2018        PMID: 30069373      PMCID: PMC6051849          DOI: 10.21037/jtd.2018.05.183

Source DB:  PubMed          Journal:  J Thorac Dis        ISSN: 2072-1439            Impact factor:   2.895


  21 in total

1.  Respiratory symptoms, spirometric respiratory impairment, and respiratory disease in middle-aged and older persons.

Authors:  Brian S Marcus; Gail McAvay; Thomas M Gill; Carlos A Vaz Fragoso
Journal:  J Am Geriatr Soc       Date:  2015-01-30       Impact factor: 5.562

Review 2.  Prevalence and assessment of breathlessness in the clinical setting.

Authors:  Miriam J Johnson; David C Currow; Sara Booth
Journal:  Expert Rev Respir Med       Date:  2014-01-22       Impact factor: 3.772

3.  The yield of a diagnostic hospital dyspnoea clinic for the primary health care section.

Authors:  L S Nielsen; J Svanegaard; P Wiggers; H Egeblad
Journal:  J Intern Med       Date:  2001-11       Impact factor: 8.989

Review 4.  The Differential Diagnosis of Dyspnea.

Authors:  Dominik Berliner; Nils Schneider; Tobias Welte; Johann Bauersachs
Journal:  Dtsch Arztebl Int       Date:  2016-12-09       Impact factor: 5.594

Review 5.  Evaluation of chronic dyspnea.

Authors:  Neel G Karnani; Gary M Reisfield; George R Wilson
Journal:  Am Fam Physician       Date:  2005-04-15       Impact factor: 3.292

6.  Revisiting signs, strengths and weaknesses of Standard Chest Radiography in patients of Acute Dyspnea in the Emergency Department.

Authors:  Luciano Cardinale; Giovanni Volpicelli; Alessandro Lamorte; Jessica Martino
Journal:  J Thorac Dis       Date:  2012-08       Impact factor: 2.895

7.  An algorithmic approach to chronic dyspnea.

Authors:  Melvin R Pratter; Wissam Abouzgheib; Stephen Akers; Jonathan Kass; Thaddeus Bartter
Journal:  Respir Med       Date:  2011-01-07       Impact factor: 3.415

8.  Graded comprehensive cardiopulmonary exercise testing in the evaluation of dyspnea unexplained by routine evaluation.

Authors:  F J Martinez; I Stanopoulos; R Acero; F S Becker; R Pickering; J F Beamis
Journal:  Chest       Date:  1994-01       Impact factor: 9.410

Review 9.  Causes and evaluation of chronic dyspnea.

Authors:  Steven A Wahls
Journal:  Am Fam Physician       Date:  2012-07-15       Impact factor: 3.292

10.  A woman with breathlessness: a practical approach to diagnosis and management.

Authors:  Alan Kaplan; Kevin Gruffydd-Jones; Frederik van Gemert; Bruce J Kirenga; Andrew R L Medford
Journal:  Prim Care Respir J       Date:  2013-12
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  4 in total

Review 1.  Diagnostic approach to chronic dyspnoea in adults.

Authors:  Olivia R Ferry; Yao C Huang; Philip J Masel; Michael Hamilton; Kwun M Fong; Rayleen V Bowman; Scott C McKenzie; Ian A Yang
Journal:  J Thorac Dis       Date:  2019-10       Impact factor: 2.895

2.  Chronic dyspnoea: finding the cause to reduce mortality.

Authors:  Gene R Pesola; Vikhyath Terla; Nasir Malik; Habibul Ahsan
Journal:  J Thorac Dis       Date:  2018-11       Impact factor: 2.895

Review 3.  Management of Refractory Breathlessness: a Review for General Internists.

Authors:  Annie Massart; Daniel P Hunt
Journal:  J Gen Intern Med       Date:  2021-01-19       Impact factor: 5.128

Review 4.  A systematic review on the effectiveness and impact of clinical decision support systems for breathlessness.

Authors:  Anthony P Sunjaya; Sameera Ansari; Christine R Jenkins
Journal:  NPJ Prim Care Respir Med       Date:  2022-08-20       Impact factor: 3.289

  4 in total

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