Literature DB >> 3006611

Rheumatoid arthritis, juvenile arthritis, iridocyclitis and the Epstein-Barr virus.

A J Gear, P J Venables, J M Edwards, R N Maini, B M Ansell.   

Abstract

In order to examine the relation of Epstein-Barry virus (EBV) infection to chronic arthritis in children antibodies to EB virus capsid antigen (EBVCA) and rheumatoid arthritis nuclear antigen (RANA) were analysed in sera from 133 patients classified as juvenile rheumatoid arthritis (JRA) or pauciarticular, polyarticular, or systemic juvenile chronic arthritis. Except for an increased frequency in the systemic subgroup, the prevalence of antibodies to EBVCA and titres of anti-RANA antibodies was similar in patients and controls. These data do not support an aetiological role for EBV in chronic arthritis in children, including JRA, and suggest that the mechanisms which may account for the higher titres of anti-RANA antibodies in adult RA do not occur in children.

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Year:  1986        PMID： 3006611      PMCID： PMC1001806          DOI： 10.1136/ard.45.1.6

Source DB:  PubMed          Journal:  Ann Rheum Dis        ISSN： 0003-4967            Impact factor:   19.103


  12 in total

1.  Serum antibody in rheumatoid arthritis reactive with a cell-associated antigen. Demonstration by precipitation and immunofluorescence.

Authors:  M A Aslpaugh; E M Tan
Journal:  Arthritis Rheum       Date:  1976 Jul-Aug

2.  Seroepidemiologic study of Epstein-Barr virus infections in a rural community.

Authors:  C V Sumaya; W Henle; G Henle; M H Smith; D LeBlanc
Journal:  J Infect Dis       Date:  1975-04       Impact factor: 5.226

Review 3.  Epstein-Barr virus. Its relationship to the pathogenesis of rheumatoid arthritis.

Authors:  J M Depper; N J Zvaifler
Journal:  Arthritis Rheum       Date:  1981-06

4.  Heberden Oration, 1977. Chronic arthritis in childhood.

Authors:  B M Ansell
Journal:  Ann Rheum Dis       Date:  1978-04       Impact factor: 19.103

5.  EB virus-specific IgA in serum of patients with infectious mononucleosis and of healthy people of different ages.

Authors:  J M Edwards; M Woodroof
Journal:  J Clin Pathol       Date:  1979-10       Impact factor: 3.411

6.  Elevated levels of antibodies to Epstein-Barr virus antigens in sera and synovial fluids of patients with rheumatoid arthritis.

Authors:  M A Alspaugh; G Henle; E T Lennette; W Henle
Journal:  J Clin Invest       Date:  1981-04       Impact factor: 14.808

7.  Seroepidemiological study of relationships between Epstein-Barr virus and rheumatoid arthritis.

Authors:  P B Ferrell; C T Aitcheson; G R Pearson; E M Tan
Journal:  J Clin Invest       Date:  1981-03       Impact factor: 14.808

8.  HLA studies in IgM rheumatoid-factor-positive arthritis of childhood.

Authors:  L E Clemens; E Albert; B M Ansell
Journal:  Ann Rheum Dis       Date:  1983-08       Impact factor: 19.103

9.  EB virus antibody at different ages.

Authors:  M S Pereira; J M Blake; A D Macrae
Journal:  Br Med J       Date:  1969-11-29

10.  Anti-RANA antibody: a marker for seronegative and seropositive rheumatoid arthritis.

Authors:  K C Ng; K A Brown; J D Perry; E J Holborow
Journal:  Lancet       Date:  1980-03-01       Impact factor: 79.321
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  3 in total

1.  Juvenile idiopathic arthritis among Nigerians: a case study.

Authors:  Olufemi O Adelowo; A Umar
Journal:  Clin Rheumatol       Date:  2010-03-01       Impact factor: 2.980

2.  Do infections trigger juvenile idiopathic arthritis?

Authors:  Mustafa Aslan; Ozgur Kasapcopur; Hatice Yasar; Erdal Polat; Suat Saribas; Huseyin Cakan; Ahmet Dirican; Müzeyyen Mamal Torun; Nil Arısoy; Bekir Kocazeybek
Journal:  Rheumatol Int       Date:  2009-12-13       Impact factor: 2.631

3.  Antibodies in rheumatoid arthritis react specifically with the glycine alanine repeat sequence of Epstein-Barr nuclear antigen-1.

Authors:  C Baboonian; D Halliday; P J Venables; T Pawlowski; G Millman; R N Maini
Journal:  Rheumatol Int       Date:  1989       Impact factor: 2.631
  3 in total

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