Literature DB >> 30065011

Hepatic thyroid hormone receptor β1 agonism: good for lipids, good for bile?

Paul A Dawson1, Paolo Parini2.   

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Year:  2018        PMID: 30065011      PMCID: PMC6121924          DOI: 10.1194/jlr.C088955

Source DB:  PubMed          Journal:  J Lipid Res        ISSN: 0022-2275            Impact factor:   5.922


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  12 in total

1.  Effects of obeticholic acid on lipoprotein metabolism in healthy volunteers.

Authors:  R Pencek; T Marmon; J D Roth; A Liberman; R Hooshmand-Rad; M A Young
Journal:  Diabetes Obes Metab       Date:  2016-06-06       Impact factor: 6.577

2.  Homozygous disruption of the murine mdr2 P-glycoprotein gene leads to a complete absence of phospholipid from bile and to liver disease.

Authors:  J J Smit; A H Schinkel; R P Oude Elferink; A K Groen; E Wagenaar; L van Deemter; C A Mol; R Ottenhoff; N M van der Lugt; M A van Roon
Journal:  Cell       Date:  1993-11-05       Impact factor: 41.582

3.  Beneficial and Adverse Effects of an LXR Agonist on Human Lipid and Lipoprotein Metabolism and Circulating Neutrophils.

Authors:  Todd G Kirchgessner; Paul Sleph; Jacek Ostrowski; John Lupisella; Carol S Ryan; Xiaoqin Liu; Gayani Fernando; Denise Grimm; Petia Shipkova; Rongan Zhang; Ricardo Garcia; Jun Zhu; Aiqing He; Harold Malone; Richard Martin; Kamelia Behnia; Zhaoqing Wang; Yu Chen Barrett; Robert J Garmise; Long Yuan; Jane Zhang; Mohit D Gandhi; Philip Wastall; Tong Li; Shuyan Du; Lisa Salvador; Raju Mohan; Glenn H Cantor; Ellen Kick; John Lee; Robert J A Frost
Journal:  Cell Metab       Date:  2016-08-09       Impact factor: 27.287

4.  Regurgitation of bile acids from leaky bile ducts causes sclerosing cholangitis in Mdr2 (Abcb4) knockout mice.

Authors:  Peter Fickert; Andrea Fuchsbichler; Martin Wagner; Gernot Zollner; Arthur Kaser; Herbert Tilg; Robert Krause; Frank Lammert; Cord Langner; Kurt Zatloukal; Hanns-Ulrich Marschall; Helmut Denk; Michael Trauner
Journal:  Gastroenterology       Date:  2004-07       Impact factor: 22.682

Review 5.  Bile formation and secretion.

Authors:  James L Boyer
Journal:  Compr Physiol       Date:  2013-07       Impact factor: 9.090

6.  Thyroid hormone differentially augments biliary sterol secretion in the rat. II. The chronic bile fistula model.

Authors:  R L Gebhard; W F Prigge
Journal:  J Lipid Res       Date:  1992-10       Impact factor: 5.922

7.  Thyroid hormone receptor β1 stimulates ABCB4 to increase biliary phosphatidylcholine excretion in mice.

Authors:  Julien Gautherot; Thierry Claudel; Frans Cuperus; Claudia Daniela Fuchs; Thomas Falguières; Michael Trauner
Journal:  J Lipid Res       Date:  2018-06-12       Impact factor: 5.922

Review 8.  Direct effects of thyroid hormones on hepatic lipid metabolism.

Authors:  Rohit A Sinha; Brijesh K Singh; Paul M Yen
Journal:  Nat Rev Endocrinol       Date:  2018-02-23       Impact factor: 43.330

9.  A comprehensive analysis of common genetic variation around six candidate loci for intrahepatic cholestasis of pregnancy.

Authors:  Peter H Dixon; Christopher A Wadsworth; Jennifer Chambers; Jennifer Donnelly; Sharon Cooley; Rebecca Buckley; Ramona Mannino; Sheba Jarvis; Argyro Syngelaki; Victoria Geenes; Priyadarshini Paul; Meera Sothinathan; Ralf Kubitz; Frank Lammert; Rachel M Tribe; Chin Lye Ch'ng; Hanns-Ulrich Marschall; Anna Glantz; Shahid A Khan; Kypros Nicolaides; John Whittaker; Michael Geary; Catherine Williamson
Journal:  Am J Gastroenterol       Date:  2013-12-24       Impact factor: 10.864

Review 10.  Potential Role of Thyroid Receptor β Agonists in the Treatment of Hyperlipidemia.

Authors:  Tomas Jakobsson; Lise-Lotte Vedin; Paolo Parini
Journal:  Drugs       Date:  2017-10       Impact factor: 9.546

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  2 in total

Review 1.  Targeting Thyroid Hormone/Thyroid Hormone Receptor Axis: An Attractive Therapy Strategy in Liver Diseases.

Authors:  Qianyu Tang; Min Zeng; Linxi Chen; Nian Fu
Journal:  Front Pharmacol       Date:  2022-06-02       Impact factor: 5.988

Review 2.  Pharmacotherapy for Non-Alcoholic Fatty Liver Disease: Emerging Targets and Drug Candidates.

Authors:  Veronika A Prikhodko; Natalia N Bezborodkina; Sergey V Okovityi
Journal:  Biomedicines       Date:  2022-01-26
  2 in total

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