Literature DB >> 30064061

Initial results of a drug checking pilot program to detect fentanyl adulteration in a Canadian setting.

Kenneth W Tupper1, Karen McCrae2, Ian Garber2, Mark Lysyshyn3, Evan Wood4.   

Abstract

BACKGROUND: Opioid overdose deaths in North America have been rising largely as a result of fentanyl adulteration in the illegal drug supply. Drug checking is an established harm reduction intervention in some European settings but has not been broadly implemented or evaluated in North America. We are evaluating a pilot program offering drug checking for people who use street drugs in Vancouver, British Columbia.
METHODS: Drug checking services were implemented at two locations in Vancouver between November 2017 and April 2018 using a Fourier transform infrared (FTIR) spectrometer and fentanyl immunoassay strips. We report on the findings generated by this technological combination during the study period.
RESULTS: During the study period, a total of 1714 samples were tested. Of 907 samples expected to be heroin, only 160 (17.6%) contained the expected substance, and 822 (90.6%) tested positive for fentanyl. Of 256 samples expected to be speed or crystal meth, 225 (87.9%) contained amphetamine or methamphetamine, and 15 (5.9%) tested positive for fentanyl. The FTIR also found unexpected and potentially dangerous substances and adulterants other than fentanyl.
CONCLUSIONS: This pilot program has demonstrated the feasibility of drug checking for identifying individual drug samples containing unexpected or hazardous substances, including fentanyl. By identifying the range of adulterants and diluents and giving an estimate of their prevalence in different drug types, it has also provided information about the composition of the illicit drug supply in an urban North American setting.
Copyright © 2018 Elsevier B.V. All rights reserved.

Entities:  

Keywords:  Drug checking; Fentanyl; Harm reduction; Opioid; Overdose; Public health

Mesh:

Substances:

Year:  2018        PMID: 30064061     DOI: 10.1016/j.drugalcdep.2018.06.020

Source DB:  PubMed          Journal:  Drug Alcohol Depend        ISSN: 0376-8716            Impact factor:   4.492


  59 in total

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4.  Applying principles of injury and infectious disease control to the opioid mortality epidemic in North America: critical intervention gaps.

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6.  Elevated prevalence of self-reported unintentional exposure to fentanyl among women who use drugs in a Canadian setting: A cross-sectional analysis.

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8.  Slow release oral morphine versus methadone for opioid use disorder in the fentanyl era (pRESTO): Protocol for a non-inferiority randomized clinical trial.

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10.  Trends in characteristics of individuals who use methamphetamine in the United States, 2015-2018.

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Journal:  Drug Alcohol Depend       Date:  2020-06-03       Impact factor: 4.492

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