Literature DB >> 30062890

Stereoselective Alkyne Hydrohalogenation by Trapping of Transfer Hydrogenation Intermediates.

Manas Das1, Trinadh Kaicharla1, Johannes F Teichert1.   

Abstract

A catalytically generated vinylcopper complex, the reactive intermediate of a copper(I)-catalyzed alkyne transfer hydrogenation, can be trapped by commercially available halogen electrophiles. In this manner, internal alkynes can stereoselectively be hydrohalogenated to the corresponding vinyl chlorides, bromides, and iodides.

Entities:  

Year:  2018        PMID： 30062890     DOI： 10.1021/acs.orglett.8b02055

Source DB:  PubMed          Journal:  Org Lett        ISSN： 1523-7052            Impact factor:   6.005


  3 in total

1.  Interplay between the Directing Group and Multifunctional Acetate Ligand in Pd-Catalyzed anti-Acetoxylation of Unsymmetrical Dialkyl-Substituted Alkynes.

Authors:  Javier Corpas; Enrique M Arpa; Romain Lapierre; Inés Corral; Pablo Mauleón; Ramón Gómez Arrayás; Juan C Carretero
Journal:  ACS Catal       Date:  2022-05-19       Impact factor: 13.700

2.  Hydroalkylation of Alkynes: Functionalization of the Alkenyl Copper Intermediate through Single Electron Transfer Chemistry.

Authors:  Avijit Hazra; Jonathan A Kephart; Alexandra Velian; Gojko Lalic
Journal:  J Am Chem Soc       Date:  2021-05-18       Impact factor: 16.383

3.  Iridium-Catalyzed Hydrochlorination and Hydrobromination of Alkynes by Shuttle Catalysis.

Authors:  Peng Yu; Alessandro Bismuto; Bill Morandi
Journal:  Angew Chem Int Ed Engl       Date:  2020-01-16       Impact factor: 15.336
  3 in total

北京卡尤迪生物科技股份有限公司 © 2022-2023.