Literature DB >> 30058699

Is fatigue a cause of work disability in systemic lupus erythematosus? Results from a systematic literature review.

F Basta1, D P E Margiotta, M Vadacca, A Vernuccio, C Mazzuca, A Picchianti Diamanti, A Afeltra.   

Abstract

OBJECTIVE: Fatigue affects the almost totality of Systemic Lupus Erythematous (SLE) patients impairing physical function and leading to a strong reduction of health-related quality of life (HRQoL). Similarly, SLE patients have an increased rate of work loss and work limitations. The aim of our paper was to systematically assess the relationship between fatigue and work disability in SLE.
MATERIALS AND METHODS: We performed a systematic review using the terms "fatigue" and "employment", "work disability", "work impairment", "presenteeism" and "absenteeism."
RESULTS: 19 studies were identified. Fatigue was involved in the development of work loss. In employed patients, fatigue led to impairment of work productivity and presenteeism with a parallel increase of both direct and indirect health costs. Fatigue also affected parenting and household productivity.
CONCLUSIONS: An adequate control of fatigue could improve physical and work performance in SLE patients thus reducing rates of work loss.

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Year:  2018        PMID: 30058699     DOI: 10.26355/eurrev_201807_15516

Source DB:  PubMed          Journal:  Eur Rev Med Pharmacol Sci        ISSN: 1128-3602            Impact factor:   3.507


  4 in total

1.  Health-related quality of life, fatigue and health utilities in lupus nephritis: A systematic literature review.

Authors:  Saifuddin Kharawala; Gavneet Kaur; Hemlata Shukla; David Alexander Scott; Neil Hawkins; Wen-Hung Chen; Kerry Gairy
Journal:  Lupus       Date:  2022-05-23       Impact factor: 2.858

2.  Impact of fatigue on health-related quality of life and illness perception in a monocentric cohort of patients with systemic lupus erythematosus.

Authors:  Elena Elefante; Chiara Tani; Chiara Stagnaro; Francesco Ferro; Alice Parma; Linda Carli; Viola Signorini; Dina Zucchi; Umberto Peta; Adele Santoni; Leonardo Raffaelli; Marta Mosca
Journal:  RMD Open       Date:  2020-02

3.  Patient Experience With Fatigue and Qualitative Interview-Based Evidence of Content Validation of The FACIT-Fatigue in Systemic Lupus Erythematosus.

Authors:  Kimberly Raymond; Josephine Park; Ashish V Joshi; Michelle K White
Journal:  Rheumatol Ther       Date:  2021-03-09

Review 4.  10 Years of belimumab experience: What have we learnt?

Authors:  Roger A Levy; Tania Gonzalez-Rivera; Munther Khamashta; Norma Lynn Fox; Angela Jones-Leone; Bernie Rubin; Susan W Burriss; Kerry Gairy; Andre van Maurik; David A Roth
Journal:  Lupus       Date:  2021-07-08       Impact factor: 2.911

  4 in total

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