Literature DB >> 30057762

Opioid prescribing in general practice: use of a two-stage review tool to identify and assess high-dose prescribing.

Rhys Ponton1, Richard Sawyer2.   

Abstract

BACKGROUND: Long-term opioid analgesic prescribing in chronic non-cancer pain (CNCP) is a growing worldwide concern. This has implications for optimal healthcare management in general and chronic pain management specifically. This work documents the development of a review tool and its use in the South West of England in a locality that showed opioid prescribing levels higher than surrounding localities.
METHODS: An electronic tool which enabled calculation of total prescribed morphine-equivalent doses was developed to allow general practitioners (GPs) to undertake reviews of CNCP patients. This tool was used to assess strong opioid prescribing over a 3-month period at every GP practice (n = 41) in the locality. Every prescription for morphine, oxycodone, pethidine and fentanyl during this period was included.Aspects assessed included drug(s) prescribed, dose prescribed, whether tramadol was prescribed concurrently, whether the drugs were potentially being overused and/or whether the patient was in palliative care. Patients prescribed over 120 mg morphine equivalent per day were reviewed in greater depth, as this is an indication for specialist input.
RESULTS: In total, 1881 patients received a prescription in the assessment period. Morphine was the most commonly prescribed drug (n = 847). In all, 363 CNCP patients were prescribed a dose equal to or above 120 mg morphine a day, with a maximum morphine-equivalent dose of 890 mg being prescribed. Over 11% (n = 211) of patients were concurrently prescribed tramadol. The most frequently cited reason for prescription of high-dose opioids was found to be a musculoskeletal pain of the back, neck, joints or limbs. The care of 85 specific CNCP patients was reviewed and optimised. DISCUSSION: No published work to date has documented such an in-depth analysis of primary-care opioid analgesic prescribing utilising prescriber data. Assessing total-dose morphine-equivalent prescribing using this method provides valuable insights into the potential need for urgent medication review. The tool developed may be of value to other GP practices following validation.

Entities:  

Keywords:  Analgesia; chronic pain; opioid analgesics; pain; pain management; primary health care

Year:  2017        PMID: 30057762      PMCID: PMC6058458          DOI: 10.1177/2049463717742420

Source DB:  PubMed          Journal:  Br J Pain        ISSN: 2049-4637


  29 in total

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2.  Opioid prescribing in the UK: can we avert a public health disaster?

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Journal:  Br J Pain       Date:  2012-02

Review 3.  Opioids for low back pain.

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Review 6.  Opioid epidemic in the United States.

Authors:  Laxmaiah Manchikanti; Standiford Helm; Bert Fellows; Jeffrey W Janata; Vidyasagar Pampati; Jay S Grider; Mark V Boswell
Journal:  Pain Physician       Date:  2012-07       Impact factor: 4.965

7.  Clinical guidelines for the use of chronic opioid therapy in chronic noncancer pain.

Authors:  Roger Chou; Gilbert J Fanciullo; Perry G Fine; Jeremy A Adler; Jane C Ballantyne; Pamela Davies; Marilee I Donovan; David A Fishbain; Kathy M Foley; Jeffrey Fudin; Aaron M Gilson; Alexander Kelter; Alexander Mauskop; Patrick G O'Connor; Steven D Passik; Gavril W Pasternak; Russell K Portenoy; Ben A Rich; Richard G Roberts; Knox H Todd; Christine Miaskowski
Journal:  J Pain       Date:  2009-02       Impact factor: 5.820

Review 8.  Opioids compared to placebo or other treatments for chronic low-back pain.

Authors:  Luis Enrique Chaparro; Andrea D Furlan; Amol Deshpande; Angela Mailis-Gagnon; Steven Atlas; Dennis C Turk
Journal:  Cochrane Database Syst Rev       Date:  2013-08-27

9.  Changes in trends and pattern of strong opioid prescribing in primary care.

Authors:  C S Zin; L C Chen; R D Knaggs
Journal:  Eur J Pain       Date:  2014-04-22       Impact factor: 3.931

Review 10.  Long-term opioid management for chronic noncancer pain.

Authors:  Meredith Noble; Jonathan R Treadwell; Stephen J Tregear; Vivian H Coates; Philip J Wiffen; Clarisse Akafomo; Karen M Schoelles
Journal:  Cochrane Database Syst Rev       Date:  2010-01-20
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Authors:  Morgane Guillou-Landreat; Bertrand Quinio; Jean Yves Le Reste; Delphine Le Goff; Jérôme Fonsecca; Marie Grall-Bronnec; Antoine Dany
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2.  Factors associated with the prescribing of high-dose opioids in primary care: a systematic review and meta-analysis.

Authors:  Georgia C Richards; Kamal R Mahtani; Tonny B Muthee; Nicholas J DeVito; Constantinos Koshiaris; Jeffrey K Aronson; Ben Goldacre; Carl J Heneghan
Journal:  BMC Med       Date:  2020-03-30       Impact factor: 8.775

  2 in total

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