Literature DB >> 30057665

Patient-perceived Emotional and Functional Benefits of Poly-L-Lactic Acid (PLLA) for the Treatment of Facial Volume Loss.

Richard Fried1,2, W Phillip Werschler1,2, Judith Cenci1,2, Lauren Sternberg1,2, Priya Dhanaraj1,2, Dara Tolas1,2, Suzanne Withrow1,2.   

Abstract

Background: Facial volume loss can substantially impact self-perception of the affected individual and his to her social/professional interactions and opportunities. Persons who are perceived as more youthful and attractive are rated as nicer, more energetic, healthier, and more likely to be productive than those perceived to be older and unattractive. Objective: The goal of this study was to assess the changes in emotional and functional status of subjects treated with 2 to 4 monthly PLLA injections to the upper, mid, and lower face.
Methods: Fifty subjects were recruited from two community dermatology centers in the United States (Bucks County, Pennsylvania, and Spokane, Washington). Two patient self-report measures were used-The Facial Volume Restoration Outcome Questionnaire and the Rosenberg Self Esteem Scale.
Results: Approximately 30 percent of the subjects who completed pre- and post-injection instruments reported increased confidence, increased sense of control, more comfort with others, increased happiness when looking in the mirror, more happiness when their faces were touched, healthier eating, increased contentment, beliefs that they were seen as less stressed by others, increased happiness with their bodies, exercising more, and that their lives were better. Additionally, 43 percent felt more optimistic and 33 percent felt less anxious. The changes in self-esteem, which was self-reported on the Rosenberg scale, were very modest but also favorable. Investigator's Global Assessment (IGA) of facial volume loss improved from 2.2 at baseline to 1.2 at six-month follow-up assessment.
Conclusion: Treatment of facial volume loss with PLLA was associated with improvements in patient-perceived emotional and functional status at six months after initial injection.

Entities:  

Keywords:  Poly-L-Lactic acid; fillers; volume loss; volume restoration

Year:  2018        PMID: 30057665      PMCID: PMC6057736     

Source DB:  PubMed          Journal:  J Clin Aesthet Dermatol        ISSN: 1941-2789


  8 in total

Review 1.  Histopathologic identification of dermal filler agents.

Authors:  Stephen E Mercer; Rebecca Kleinerman; Gary Goldenberg; Patrick O Emanuel
Journal:  J Drugs Dermatol       Date:  2010-09       Impact factor: 2.114

2.  The botulinum toxin experience: results of a patient self-report questionnaire.

Authors:  Richard G Fried; Wm Philip Werschler; Tracy Floirendo
Journal:  J Clin Aesthet Dermatol       Date:  2009-11

Review 3.  Facial volume restoration of the aging face with poly-l-lactic acid.

Authors:  Rebecca Fitzgerald; Danny Vleggaar
Journal:  Dermatol Ther       Date:  2011 Jan-Feb       Impact factor: 2.851

4.  Filler cheeks: a bright idea? The "eyes" have it.

Authors:  Richard G Fried
Journal:  J Clin Aesthet Dermatol       Date:  2011-05

5.  Satisfying patient expectations with poly-L-lactic acid soft tissue augmentation.

Authors:  Danny Vleggaar; Rebecca Fitzgerald; Z Paul Lorenc
Journal:  J Drugs Dermatol       Date:  2014-04       Impact factor: 2.114

6.  Current Applications of Facial Volumization with Fillers.

Authors:  Anthony J Wilson; Anthony J Taglienti; Catherine S Chang; David W Low; Ivona Percec
Journal:  Plast Reconstr Surg       Date:  2016-05       Impact factor: 4.730

7.  A Randomized, Controlled, Multicenter Study of Juvéderm Voluma for Enhancement of Malar Volume in Chinese Subjects.

Authors:  Dong Li; Xiaojun Wang; Yan Wu; Jiaming Sun; Qin Li; Shuzhong Guo; Yi Jia; Diane K Murphy
Journal:  Plast Reconstr Surg       Date:  2017-06       Impact factor: 4.730

8.  Current Trends in Facial Rejuvenation with Fillers.

Authors:  Shehnaz Z Arsiwala
Journal:  J Cutan Aesthet Surg       Date:  2015 Jul-Sep
  8 in total

北京卡尤迪生物科技股份有限公司 © 2022-2023.