Ozge Sarac1, Pinar Kosekahya2, Mehtap Caglayan2, Burak Tanriverdi2, Ayse Güzin Taslipinar Uzel2, Nurullah Cagil2. 1. From the Departments of Ophthalmology, Yildirim Beyazit University, Ankara Atatürk Training and Research Hospital (Sarac, Tanriverdi, Cagil), Ulucanlar Eye Training and Research Hospital (Kosekahya), Ankara, Gazi Yasargil Training and Research Hospital (Caglayan), Diyarbakir, and Afyon Sandikli State Hospital (Uzel), Afyon, Turkey. Electronic address: drozgesarac@gmail.com. 2. From the Departments of Ophthalmology, Yildirim Beyazit University, Ankara Atatürk Training and Research Hospital (Sarac, Tanriverdi, Cagil), Ulucanlar Eye Training and Research Hospital (Kosekahya), Ankara, Gazi Yasargil Training and Research Hospital (Caglayan), Diyarbakir, and Afyon Sandikli State Hospital (Uzel), Afyon, Turkey.
Abstract
PURPOSE: To compare the 36-month outcomes of mechanical or transepithelial phototherapeutic keratectomy (PTK) epithelial removal before accelerated corneal crosslinking (CXL) for pediatric keratoconus. SETTING: Atatürk Training and Research Hospital, Ankara, Turkey. DESIGN: Retrospective case series. METHODS: Eyes that had accelerated CXL after mechanical (Group 1) or transepithelial PTK (Group 2) epithelial removal were evaluated preoperatively and 12, 24, and 36 months postoperatively. The uncorrected (UDVA) and corrected distance visual acuities, spherical equivalent (SE), manifest astigmatism, and corneal tomographic and aberrometric parameters were assessed. RESULTS: The study included 40 eyes of 35 consecutive keratoconus patients younger than 18 years with a 36-month follow-up. Group 1 comprised 15 patients, and Group 2 comprised 20 patients. Both groups had a significant improvement in UDVA (P = .001 and P = .02, respectively) and a significant decrease in maximum keratometry (K) and thinnest corneal thickness (all P < .001) 36 months postoperatively. The improvements in maximum K, topographic astigmatism, and spherical aberration were greater in Group 2 than in Group 1 at 12 months (P = .03, P = .01, and P = .04, respectively). After 12 months, the outcomes in the 2 groups were more similar. CONCLUSIONS: The initial visual and topographic outcomes of transepithelial PTK ablation were better than those of mechanical epithelium removal before accelerated CXL in pediatric patients with keratoconus. Over the long-term, the results were similar between the 2 groups.
PURPOSE: To compare the 36-month outcomes of mechanical or transepithelial phototherapeutic keratectomy (PTK) epithelial removal before accelerated corneal crosslinking (CXL) for pediatric keratoconus. SETTING: Atatürk Training and Research Hospital, Ankara, Turkey. DESIGN: Retrospective case series. METHODS: Eyes that had accelerated CXL after mechanical (Group 1) or transepithelial PTK (Group 2) epithelial removal were evaluated preoperatively and 12, 24, and 36 months postoperatively. The uncorrected (UDVA) and corrected distance visual acuities, spherical equivalent (SE), manifest astigmatism, and corneal tomographic and aberrometric parameters were assessed. RESULTS: The study included 40 eyes of 35 consecutive keratoconus patients younger than 18 years with a 36-month follow-up. Group 1 comprised 15 patients, and Group 2 comprised 20 patients. Both groups had a significant improvement in UDVA (P = .001 and P = .02, respectively) and a significant decrease in maximum keratometry (K) and thinnest corneal thickness (all P < .001) 36 months postoperatively. The improvements in maximum K, topographic astigmatism, and spherical aberration were greater in Group 2 than in Group 1 at 12 months (P = .03, P = .01, and P = .04, respectively). After 12 months, the outcomes in the 2 groups were more similar. CONCLUSIONS: The initial visual and topographic outcomes of transepithelial PTK ablation were better than those of mechanical epithelium removal before accelerated CXL in pediatric patients with keratoconus. Over the long-term, the results were similar between the 2 groups.
Authors: Jurriaan Brekelmans; Mor M Dickman; Shwetabh Verma; Samuel Arba-Mosquera; Ruth Goldschmidt; Alexandra Goz; Alexander Brandis; Tos T J M Berendschot; Isabelle E Y Saelens; Arie L Marcovich; Avigdor Scherz; Rudy M M A Nuijts Journal: Acta Ophthalmol Date: 2021-09-17 Impact factor: 3.988
Authors: Vardhaman P Kankariya; Ankita B Dube; Michael A Grentzelos; George A Kontadakis; Vasilios F Diakonis; Myrsini Petrelli; George D Kymionis Journal: Indian J Ophthalmol Date: 2020-12 Impact factor: 1.848