Literature DB >> 30053423

Whirling Platelets Away for Transfusion.

Camelia Iancu-Rubin1, Ronald Hoffman1, Anna Rita Migliaccio2.   

Abstract

With a growing demand for platelet transfusions, large-scale ex vivo platelet production would alleviate the reliance on donors. Now, Ito et al. report that turbulence is an important physical regulator of platelet generation in vivo and can be exploited in a bioreactor to enable clinical scale production of functional platelets starting from human iPSCs.
Copyright © 2018 Elsevier Inc. All rights reserved.

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Year:  2018        PMID： 30053423      PMCID： PMC6487281          DOI： 10.1016/j.cell.2018.07.018

Source DB:  PubMed          Journal:  Cell        ISSN： 0092-8674            Impact factor:   41.582


  8 in total

Review 1.  Platelet transfusion: a systematic review of the clinical evidence.

Authors:  Ambuj Kumar; Rahul Mhaskar; Brenda J Grossman; Richard M Kaufman; Aaron A R Tobian; Steven Kleinman; Terry Gernsheimer; Alan T Tinmouth; Benjamin Djulbegovic
Journal:  Transfusion       Date:  2014-11-12       Impact factor: 3.157

Review 2.  Ex vivo production of platelets from stem cells.

Authors:  Mauro P Avanzi; William Beau Mitchell
Journal:  Br J Haematol       Date:  2014-02-13       Impact factor: 6.998

3.  Comparative analysis of human ex vivo-generated platelets vs megakaryocyte-generated platelets in mice: a cautionary tale.

Authors:  Yuhuan Wang; Vincent Hayes; Danuta Jarocha; Xiuli Sim; Dawn C Harper; Rudy Fuentes; Spencer K Sullivan; Paul Gadue; Stella T Chou; Beverly J Torok-Storb; Michael S Marks; Deborah L French; Mortimer Poncz
Journal:  Blood       Date:  2015-04-07       Impact factor: 22.113

Review 4.  Platelet bioreactor: accelerated evolution of design and manufacture.

Authors:  Jonathan N Thon; Brad J Dykstra; Lea M Beaulieu
Journal:  Platelets       Date:  2017-01-23       Impact factor: 3.862

Review 5.  Challenges and promises for the development of donor-independent platelet transfusions.

Authors:  Michele P Lambert; Spencer K Sullivan; Rudy Fuentes; Deborah L French; Mortimer Poncz
Journal:  Blood       Date:  2013-01-15       Impact factor: 22.113

6.  Expandable megakaryocyte cell lines enable clinically applicable generation of platelets from human induced pluripotent stem cells.

Authors:  Sou Nakamura; Naoya Takayama; Shinji Hirata; Hideya Seo; Hiroshi Endo; Kiyosumi Ochi; Ken-ichi Fujita; Tomo Koike; Ken-ichi Harimoto; Takeaki Dohda; Akira Watanabe; Keisuke Okita; Nobuyasu Takahashi; Akira Sawaguchi; Shinya Yamanaka; Hiromitsu Nakauchi; Satoshi Nishimura; Koji Eto
Journal:  Cell Stem Cell       Date:  2014-02-13       Impact factor: 24.633

7.  Turbulence Activates Platelet Biogenesis to Enable Clinical Scale Ex Vivo Production.

Authors:  Yukitaka Ito; Sou Nakamura; Naoshi Sugimoto; Tomohiro Shigemori; Yoshikazu Kato; Mikiko Ohno; Shinya Sakuma; Keitaro Ito; Hiroki Kumon; Hidenori Hirose; Haruki Okamoto; Masayuki Nogawa; Mio Iwasaki; Shunsuke Kihara; Kosuke Fujio; Takuya Matsumoto; Natsumi Higashi; Kazuya Hashimoto; Akira Sawaguchi; Ken-Ichi Harimoto; Masato Nakagawa; Takuya Yamamoto; Makoto Handa; Naohide Watanabe; Eiichiro Nishi; Fumihito Arai; Satoshi Nishimura; Koji Eto
Journal:  Cell       Date:  2018-07-12       Impact factor: 41.582

8.  Infusion of megakaryocytic progenitor products generated from cord blood hematopoietic stem/progenitor cells: results of the phase 1 study.

Authors:  Jiafei Xi; Honghu Zhu; Daqing Liu; Xue Nan; Wen Zheng; Kaiyan Liu; Wei Shi; Lin Chen; Yang Lv; Fang Yan; Yanhua Li; Xiaoyan Xie; Yunfang Wang; Wen Yue; Xin Xu; Xiaofei Wei; Jun Zhu; Xiaojun Huang; Xuetao Pei
Journal:  PLoS One       Date:  2013-02-04       Impact factor: 3.240
  8 in total
  1 in total

1.  Shared and Distinctive Ultrastructural Abnormalities Expressed by Megakaryocytes in Bone Marrow and Spleen From Patients With Myelofibrosis.

Authors:  Maria Zingariello; Vittorio Rosti; Alessandro M Vannucchi; Paola Guglielmelli; Maria Mazzarini; Giovanni Barosi; Maria Luisa Genova; Anna Rita Migliaccio
Journal:  Front Oncol       Date:  2020-11-16       Impact factor: 6.244
  1 in total

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