Literature DB >> 30052150

Lateral lumbar interbody fusion in the elderly: a 10-year experience.

Nitin Agarwal, Andrew Faramand, Nima Alan, Zachary J Tempel, D Kojo Hamilton, David O Okonkwo, Adam S Kanter.   

Abstract

OBJECTIVEElderly patients, often presenting with multiple medical comorbidities, are touted to be at an increased risk of peri- and postoperative complications following spine surgery. Various minimally invasive surgical techniques have been developed and employed to treat an array of spinal conditions while minimizing complications. Lateral lumbar interbody fusion (LLIF) is one such approach. The authors describe clinical outcomes in patients over the age of 70 years following stand-alone LLIF.METHODSA retrospective query of a prospectively maintained database was performed for patients over the age of 70 years who underwent stand-alone LLIF. Patients with posterior segmental fixation and/or fusion were excluded. The preoperative and postoperative values for the Oswestry Disability Index (ODI) were analyzed to compare outcomes after intervention. Femoral neck t-scores were acquired from bone density scans and correlated with the incidence of graft subsidence.RESULTSAmong the study cohort of 55 patients, the median age at the time of surgery was 74 years (range 70-87 years). Seventeen patients had at least 3 medical comorbidities at surgery. Twenty-three patients underwent a 1-level, 14 a 2-level, and 18 patients a 3-level or greater stand-alone lateral fusion. The median estimated blood loss was 25 ml (range 5-280 ml). No statistically significant relationship was detected between volume of blood loss and the number of operative levels. The median length of hospital stay was 2 days (range 1-4 days). No statistically significant relationship was observed between the length of hospital stay and age at the time of surgery. There was one intraoperative death secondary to cardiac arrest, with a mortality rate of 1.8%. One patient developed a transient femoral nerve injury. Five patients with symptomatic graft subsidence subsequently underwent posterior instrumentation. A lower femoral neck t-score < -1.0 correlated with a higher incidence of graft subsidence (p = 0.006). The mean ODI score 1 year postoperatively of 31.1 was significantly (p = 0.003) less than the mean preoperative ODI score of 46.2.CONCLUSIONSStand-alone LLIF can be safely and effectively performed in the elderly population. Careful evaluation of preoperative bone density parameters should be employed to minimize risk of subsidence and need for additional surgery. Despite an association with increased comorbidities, age alone should not be a deterrent when considering stand-alone LLIF in the elderly population.

Entities:  

Keywords:  ALIF = anterior lumbar interbody fusion; EBL = estimated blood loss; LLIF = lateral lumbar interbody fusion; ODI = Oswestry Disability Index; PLIF = posterior lumbar interbody fusion; TLIF = transforaminal lumbar interbody fusion; complications; elderly; lateral lumbar interbody fusion; outcomes

Mesh:

Year:  2018        PMID: 30052150     DOI: 10.3171/2018.3.SPINE171147

Source DB:  PubMed          Journal:  J Neurosurg Spine        ISSN: 1547-5646


  6 in total

Review 1.  Current state of minimally invasive spine surgery.

Authors:  Avani S Vaishnav; Yahya A Othman; Sohrab S Virk; Catherine Himo Gang; Sheeraz A Qureshi
Journal:  J Spine Surg       Date:  2019-06

Review 2.  Incidence of major and minor vascular injuries during lateral access lumbar interbody fusion procedures: a retrospective comparative study and systematic literature review.

Authors:  Alexander O Aguirre; Mohamed A R Soliman; Shady Azmy; Asham Khan; Patrick K Jowdy; Jeffrey P Mullin; John Pollina
Journal:  Neurosurg Rev       Date:  2021-12-01       Impact factor: 3.042

3.  Development of a decision-making pathway for utilizing standalone lateral lumbar interbody fusion.

Authors:  Dominik Adl Amini; Manuel Moser; Lisa Oezel; Jiaqi Zhu; Jennifer Shue; Andrew A Sama; Frank P Cammisa; Federico P Girardi; Alexander P Hughes
Journal:  Eur Spine J       Date:  2021-10-28       Impact factor: 2.721

4.  Differences in radiographic and clinical outcomes of oblique lateral interbody fusion and lateral lumbar interbody fusion for degenerative lumbar disease: a meta-analysis.

Authors:  Hui-Min Li; Ren-Jie Zhang; Cai-Liang Shen
Journal:  BMC Musculoskelet Disord       Date:  2019-12-04       Impact factor: 2.362

Review 5.  Comparison of Lumbar Laminectomy Alone, Lumbar Laminectomy and Fusion, Stand-alone Anterior Lumbar Interbody Fusion, and Stand-alone Lateral Lumbar Interbody Fusion for Treatment of Lumbar Spinal Stenosis: A Review of the Literature.

Authors:  Manan Shah; Bradley Kolb; Emre Yilmaz; Dia R Halalmeh; Marc D Moisi
Journal:  Cureus       Date:  2019-09-18

6.  Prognostic Bone Metastasis-Associated Immune-Related Genes Regulated by Transcription Factors in Mesothelioma.

Authors:  Zhiquan Hao; Siqiao Wang; Zixuan Zheng; Jiehan Li; Wanting Fu; Donglin Han; Yinrou Huang; Qing Lin; Shuyuan Xian; Penghui Yan; Man Li; Ruoyi Lin; Tong Meng; Jie Zhang; Zongqiang Huang
Journal:  Biomed Res Int       Date:  2022-01-27       Impact factor: 3.411

  6 in total

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