M Bombelli1,2, Rita Facchetti1, Giuseppe Mancia1, Guido Grassi3,4. 1. Department of Medicine and Surgery, University of Milano-Bicocca, Via Pergolesi 33, 20052, Monza (Milan), Italy. 2. Clinica Medica, Ospedale San Gerardo dei Tintori, Monza (Milan), Italy. 3. Department of Medicine and Surgery, University of Milano-Bicocca, Via Pergolesi 33, 20052, Monza (Milan), Italy. guido.grassi@unimib.it. 4. Istituto di Ricerche a Carattere Scientifico Multimedica, Sesto San Giovanni, Milan, Italy. guido.grassi@unimib.it.
Abstract
PURPOSE OF REVIEW: The paper examines the patterns of BP control achieved in two large scale observational studies, i.e., the Pressioni Arteriose Monitorate E Loro Associazioni (PAMELA) study and the Blood Pressure control rate and CArdiovascular Risk profilE (BP-CARE), carried out in the general population and in treated hypertensive patients, respectively. RECENT FINDINGS: It is well known that only a minor fraction among the treated hypertensive patients exhibits a good blood pressure control. However, few study investigated blood pressure control on the basis not only of office, but also home and ambulatory blood pressure measurement, examining its impact on organ damage. In the whole sample of the PAMELA study, only in about 21.1% of cases treated hypertensive subjects exhibit a well-controlled office BP. Control of systolic blood pressure was rarer than the diastolic one. Control of home and, even more, ambulatory blood pressure was more frequent. Left ventricular mass was not normalized even when blood pressure was adequately controlled. Most subjects of BP-CARE study show high or very high cardiovascular risk, due to concomitant risk factors and organ damage. The percentage of well-treated hypertensive patients is lower when CV risk is higher.
PURPOSE OF REVIEW: The paper examines the patterns of BP control achieved in two large scale observational studies, i.e., the Pressioni Arteriose Monitorate E Loro Associazioni (PAMELA) study and the Blood Pressure control rate and CArdiovascular Risk profilE (BP-CARE), carried out in the general population and in treated hypertensivepatients, respectively. RECENT FINDINGS: It is well known that only a minor fraction among the treated hypertensivepatients exhibits a good blood pressure control. However, few study investigated blood pressure control on the basis not only of office, but also home and ambulatory blood pressure measurement, examining its impact on organ damage. In the whole sample of the PAMELA study, only in about 21.1% of cases treated hypertensive subjects exhibit a well-controlled office BP. Control of systolic blood pressure was rarer than the diastolic one. Control of home and, even more, ambulatory blood pressure was more frequent. Left ventricular mass was not normalized even when blood pressure was adequately controlled. Most subjects of BP-CARE study show high or very high cardiovascular risk, due to concomitant risk factors and organ damage. The percentage of well-treated hypertensivepatients is lower when CV risk is higher.
Entities:
Keywords:
Ambulatory blood pressure; Blood pressure control; Home blood pressure; Office blood pressure; Organ damage
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