Literature DB >> 30050119

YAP/TAZ upstream signals and downstream responses.

Antonio Totaro1, Tito Panciera1, Stefano Piccolo2,3.   

Abstract

Cell behaviour is strongly influenced by physical, mechanical contacts between cells and their extracellular matrix. We review how the transcriptional regulators YAP and TAZ integrate mechanical cues with the response to soluble signals and metabolic pathways to control multiple aspects of cell behaviour, including proliferation, cell plasticity and stemness essential for tissue regeneration. Corruption of cell-environment interplay leads to aberrant YAP and TAZ activation that is instrumental for multiple diseases, including cancer.

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Year:  2018        PMID： 30050119      PMCID： PMC6186418          DOI： 10.1038/s41556-018-0142-z

Source DB:  PubMed          Journal:  Nat Cell Biol        ISSN： 1465-7392            Impact factor:   28.824


  159 in total

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Authors:  Bing Hu; Einar Castillo; Louise Harewood; Paola Ostano; Alexandre Reymond; Reinhard Dummer; Wassim Raffoul; Wolfram Hoetzenecker; Günther F L Hofbauer; G Paolo Dotto
Journal:  Cell       Date:  2012-06-08       Impact factor: 41.582

Review 2.  Local force and geometry sensing regulate cell functions.

Authors:  Viola Vogel; Michael Sheetz
Journal:  Nat Rev Mol Cell Biol       Date:  2006-04       Impact factor: 94.444

Review 3.  Sensing the local environment: actin architecture and Hippo signalling.

Authors:  Pedro Gaspar; Nicolas Tapon
Journal:  Curr Opin Cell Biol       Date:  2014-09-25       Impact factor: 8.382

4.  Role of YAP/TAZ in mechanotransduction.

Authors:  Sirio Dupont; Leonardo Morsut; Mariaceleste Aragona; Elena Enzo; Stefano Giulitti; Michelangelo Cordenonsi; Francesca Zanconato; Jimmy Le Digabel; Mattia Forcato; Silvio Bicciato; Nicola Elvassore; Stefano Piccolo
Journal:  Nature       Date:  2011-06-08       Impact factor: 49.962

5.  Defects in yolk sac vasculogenesis, chorioallantoic fusion, and embryonic axis elongation in mice with targeted disruption of Yap65.

Authors:  Elizabeth M Morin-Kensicki; Brian N Boone; Michael Howell; Jaclyn R Stonebraker; Jeremy Teed; James G Alb; Terry R Magnuson; Wanda O'Neal; Sharon L Milgram
Journal:  Mol Cell Biol       Date:  2006-01       Impact factor: 4.272

Review 6.  Mechanotransduction and extracellular matrix homeostasis.

Authors:  Jay D Humphrey; Eric R Dufresne; Martin A Schwartz
Journal:  Nat Rev Mol Cell Biol       Date:  2014-10-22       Impact factor: 94.444

Review 7.  Why don't we get more cancer? A proposed role of the microenvironment in restraining cancer progression.

Authors:  Mina J Bissell; William C Hines
Journal:  Nat Med       Date:  2011-03       Impact factor: 53.440

Review 8.  Balancing forces: architectural control of mechanotransduction.

Authors:  Christopher C DuFort; Matthew J Paszek; Valerie M Weaver
Journal:  Nat Rev Mol Cell Biol       Date:  2011-05       Impact factor: 94.444

Review 9.  Mechanobiology of YAP and TAZ in physiology and disease.

Authors:  Tito Panciera; Luca Azzolin; Michelangelo Cordenonsi; Stefano Piccolo
Journal:  Nat Rev Mol Cell Biol       Date:  2017-09-27       Impact factor: 94.444

Review 10.  YAP/TAZ at the Roots of Cancer.

Authors:  Francesca Zanconato; Michelangelo Cordenonsi; Stefano Piccolo
Journal:  Cancer Cell       Date:  2016-06-13       Impact factor: 31.743
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  205 in total

1.  Matrix mechanotransduction mediated by thrombospondin-1/integrin/YAP in the vascular remodeling.

Authors:  Yoshito Yamashiro; Bui Quoc Thang; Karina Ramirez; Seung Jae Shin; Tomohiro Kohata; Shigeaki Ohata; Tram Anh Vu Nguyen; Sumio Ohtsuki; Kazuaki Nagayama; Hiromi Yanagisawa
Journal:  Proc Natl Acad Sci U S A       Date:  2020-04-22       Impact factor: 11.205

2.  Nucleocytoplasmic Shuttling of the Mechanosensitive Transcription Factors MRTF and YAP /TAZ.

Authors:  Michael Kofler; András Kapus
Journal:  Methods Mol Biol       Date:  2021

3.  UBTD1 is a mechano-regulator controlling cancer aggressiveness.

Authors:  Stéphanie Torrino; François-René Roustan; Lisa Kaminski; Thomas Bertero; Sabrina Pisano; Damien Ambrosetti; Maeva Dufies; Jay P Uhler; Emmanuel Lemichez; Amel Mettouchi; Maeva Gesson; Kathiane Laurent; Cedric Gaggioli; Jean-Francois Michiels; Christophe Lamaze; Frédéric Bost; Stéphan Clavel
Journal:  EMBO Rep       Date:  2019-02-25       Impact factor: 8.807

4.  High expression of the transcriptional coactivator TAZ is associated with a worse prognosis and affects cell proliferation in patients with medulloblastoma.

Authors:  Hao Wang; Ji Zhou; Dong Yang; Liang Yi; Xuhui Wang; Yangqing Ou; Donghong Yang; Lunshan Xu; Minhui Xu
Journal:  Oncol Lett       Date:  2019-09-11       Impact factor: 2.967

5.  cTAZ: a safeguard factor of antiviral response.

Authors:  Sabrina Strano; Giovanni Blandino
Journal:  EMBO Rep       Date:  2019-04-17       Impact factor: 8.807

Review 6.  Regulation of breast cancer metastasis signaling by miRNAs.

Authors:  Belinda J Petri; Carolyn M Klinge
Journal:  Cancer Metastasis Rev       Date:  2020-09       Impact factor: 9.264

Review 7.  The liver fibrosis niche: Novel insights into the interplay between fibrosis-composing mesenchymal cells, immune cells, endothelial cells, and extracellular matrix.

Authors:  Michitaka Matsuda; Ekihiro Seki
Journal:  Food Chem Toxicol       Date:  2020-07-05       Impact factor: 6.023

8.  SLIT3 deficiency attenuates pressure overload-induced cardiac fibrosis and remodeling.

Authors:  Lianghui Gong; Shuyun Wang; Li Shen; Catherine Liu; Mena Shenouda; Baolei Li; Xiaoxiao Liu; John A Shaw; Alan L Wineman; Yifeng Yang; Dingding Xiong; Anne Eichmann; Sylvia M Evans; Stephen J Weiss; Ming-Sing Si
Journal:  JCI Insight       Date:  2020-06-18

Review 9.  The role of Piezo proteins and cellular mechanosensing in tuning the fate of transplanted stem cells.

Authors:  Abolfazl Barzegari; Yadollah Omidi; Alireza Ostadrahimi; Virginie Gueguen; Anne Meddahi-Pellé; Mohammad Nouri; Graciela Pavon-Djavid
Journal:  Cell Tissue Res       Date:  2020-03-25       Impact factor: 5.249

10.  Genome-wide RNA interference screening reveals a COPI-MAP2K3 pathway required for YAP regulation.

Authors:  Yong Joon Kim; Eunji Jung; Eunbie Shin; Sin-Hyoung Hong; Hui Su Jeong; Gayeong Hur; Hye Yun Jeong; Seung-Hyo Lee; Ji Eun Lee; Gun-Hwa Kim; Joon Kim
Journal:  Proc Natl Acad Sci U S A       Date:  2020-08-03       Impact factor: 11.205
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