Literature DB >> 3004995

Effect of ACTH-(4-10) on equilibrium compensation after unilateral labyrinthectomy in the squirrel monkey.

M Igarashi, K Ishikawa, M Ishii, K A Schmidt.   

Abstract

Daily injection of ACTH-(4-10) was given to squirrel monkeys for a 28 day period to modify the characteristics of the post-unilateral labyrinthectomy symptoms along the course of the equilibrium compensation. When compared to the results of the control group, the ACTH-(4-10) injection groups (daily dose 250 micrograms/kg or 500 micrograms/kg) showed a significant improvement of acquisition and maintenance of compensation both in the spinal locomotor balance function and the oculomotor balance function.

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Year:  1985        PMID： 3004995     DOI： 10.1016/0014-2999(85)90302-4

Source DB:  PubMed          Journal:  Eur J Pharmacol        ISSN： 0014-2999            Impact factor:   4.432


  4 in total

Review 1.  Molecular mechanisms of brainstem plasticity. The vestibular compensation model.

Authors:  C L Darlington; H Flohr; P F Smith
Journal:  Mol Neurobiol       Date:  1991       Impact factor: 5.590

2.  A dose-response analysis of the beneficial effects of the ACTH-(4-9) analogue, Org 2766, on behavioural recovery following unilateral labyrinthectomy in guinea-pig.

Authors:  D P Gilchrist; C L Darlington; P F Smith
Journal:  Br J Pharmacol       Date:  1994-01       Impact factor: 8.739

3.  Guinea pig medial vestibular nucleus neurons in vitro respond to ACTH4-10 at picomolar concentrations.

Authors:  C L Darlington; P F Smith; J I Hubbard
Journal:  Exp Brain Res       Date:  1990       Impact factor: 1.972

4.  Interactions between Stress and Vestibular Compensation - A Review.

Authors:  Yougan Saman; D E Bamiou; Michael Gleeson; Mayank B Dutia
Journal:  Front Neurol       Date:  2012-07-27       Impact factor: 4.003
  4 in total

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