Literature DB >> 30047000

Immunodeficiency in Patients with Acute Exacerbation of Chronic Obstructive Pulmonary Disease.

Sheling Xie1, Kaifei Wang1, Wei Zhang1, Kun Xiao1, Peng Yan1, Yanqin Li1, Wanxue He1, Yuhan Zhang2, Lixin Xie3.   

Abstract

Chronic obstructive pulmonary disease (COPD), characterized by progressive airway inflammation and irreversible airflow limitation, leads to serious decline in life quality. The acute exacerbation of COPD (AECOPD) results in high healthcare costs as well as a significant mortality rate. The most common cause of acute exacerbation is infection. Immune deficiency, which induces dysfunction of anti-infection, plays an important role in the pathogenesis of acute exacerbation. As described in this review, the immune dysfunction in patients with AECOPD can be a major focus of efforts to therapeutic strategy.

Entities:  

Keywords:  acute exacerbation of chronic obstructive pulmonary disease; adaptive immunity; chronic obstructive pulmonary disease; immune deficiency; immunodeficiency; inflammation; innate immunity

Mesh：

Year:  2018        PMID： 30047000     DOI： 10.1007/s10753-018-0830-7

Source DB:  PubMed          Journal:  Inflammation        ISSN： 0360-3997            Impact factor:   4.092


  83 in total

Review 1.  Alternative activation of macrophages: an immunologic functional perspective.

Authors:  Fernando O Martinez; Laura Helming; Siamon Gordon
Journal:  Annu Rev Immunol       Date:  2009       Impact factor: 28.527

2.  Increased CTLA-4+ T cells may contribute to impaired T helper type 1 immune responses in patients with chronic obstructive pulmonary disease.

Authors:  Dino B A Tan; Teck-Hui Teo; Abdul M Setiawan; Nathanael E Ong; Maja Zimmermann; Patricia Price; Lea-Ann S Kirkham; Yuben P Moodley
Journal:  Immunology       Date:  2017-03-20       Impact factor: 7.397

Review 3.  Defective phagocytosis in airways disease.

Authors:  Louise E Donnelly; Peter J Barnes
Journal:  Chest       Date:  2012-04       Impact factor: 9.410

Review 4.  T helper cells plasticity in inflammation.

Authors:  Lorenzo Cosmi; Laura Maggi; Veronica Santarlasci; Francesco Liotta; Francesco Annunziato
Journal:  Cytometry A       Date:  2013-09-05       Impact factor: 4.355

5.  A Sputum Proteomic Signature That Associates with Increased IL-1β Levels and Bacterial Exacerbations of COPD.

Authors:  Gautam Damera; Tuyet-Hang Pham; Jianchun Zhang; Christine K Ward; Paul Newbold; Koustubh Ranade; Sanjay Sethi
Journal:  Lung       Date:  2016-04-15       Impact factor: 2.584

6.  Cytokine-mediated Bax deficiency and consequent delayed neutrophil apoptosis: a general mechanism to accumulate effector cells in inflammation.

Authors:  B Dibbert; M Weber; W H Nikolaizik; P Vogt; M H Schöni; K Blaser; H U Simon
Journal:  Proc Natl Acad Sci U S A       Date:  1999-11-09       Impact factor: 11.205

7.  A single dose of lipopolysaccharide into mice with emphysema mimics human chronic obstructive pulmonary disease exacerbation as assessed by micro-computed tomography.

Authors:  Satoshi Kobayashi; Reiko Fujinawa; Fumi Ota; Shiho Kobayashi; Takashi Angata; Manabu Ueno; Toshitaka Maeno; Shinobu Kitazume; Keiichi Yoshida; Takeo Ishii; Congxiao Gao; Kazuaki Ohtsubo; Yoshiki Yamaguchi; Tomoko Betsuyaku; Kozui Kida; Naoyuki Taniguchi
Journal:  Am J Respir Cell Mol Biol       Date:  2013-12       Impact factor: 6.914

Review 8.  Inflammation and immune response in COPD: where do we stand?

Authors:  Nikoletta Rovina; Antonia Koutsoukou; Nikolaos G Koulouris
Journal:  Mediators Inflamm       Date:  2013-07-15       Impact factor: 4.711

9.  Mechanisms of corticosteroid insensitivity in COPD alveolar macrophages exposed to NTHi.

Authors:  Rana M Khalaf; Simon R Lea; Hannah J Metcalfe; Dave Singh
Journal:  Respir Res       Date:  2017-04-18

10.  Detection of multiple viral and bacterial infections in acute exacerbation of chronic obstructive pulmonary disease: a pilot prospective study.

Authors:  Jeanne-Marie Perotin; Sandra Dury; Fanny Renois; Gaëtan Deslee; Aurore Wolak; Véronique Duval; Christophe De Champs; François Lebargy; Laurent Andreoletti
Journal:  J Med Virol       Date:  2013-02-27       Impact factor: 2.327
View more
  4 in total

1.  Long non-coding RNA NEAT1 predicts elevated chronic obstructive pulmonary disease (COPD) susceptibility and acute exacerbation risk, and correlates with higher disease severity, inflammation, and lower miR-193a in COPD patients.

Authors:  Xiaoyan Ming; Weizhe Duan; Wei Yi
Journal:  Int J Clin Exp Pathol       Date:  2019-08-01

2.  Associations Between Sputum Torque Teno Virus Load and Lung Function and Disease Severity in Patients With Chronic Obstructive Pulmonary Disease.

Authors:  Yu Xie; Qing Xue; Weike Jiao; Jianhui Wu; Yan Yu; Lili Zhao; Yu Xu; Xinyu Deng; Guiju Fang; Yali Zheng; Zhancheng Gao
Journal:  Front Med (Lausanne)       Date:  2021-04-22

3.  Increased Serum Soluble Interleukin-2 Receptor Associated with Severity of Acute Exacerbation of Chronic Obstructive Pulmonary Disease.

Authors:  Yue Zhang; Lianping Ren; Jinyuan Sun; Fengfeng Han; Xuejun Guo
Journal:  Int J Chron Obstruct Pulmon Dis       Date:  2021-09-07

4.  Application of Artificial Intelligence in Emergency Nursing of Patients with Chronic Obstructive Pulmonary Disease.

Authors:  Lingzhi Hong; Xufang Cheng; Deming Zheng
Journal:  Contrast Media Mol Imaging       Date:  2021-11-24       Impact factor: 3.161
  4 in total

北京卡尤迪生物科技股份有限公司 © 2022-2023.