Literature DB >> 3004557

Antibodies to herpes simplex virus type I in intraocular fluids of patients with acute retinal necrosis.

N Sarkies, Z Gregor, T Forsey, S Darougar.   

Abstract

The intraocular fluids and sera from three patients with acute retinal necrosis (ARN) and from 120 age-matched controls were tested for the presence of antibodies to herpes simplex virus type I (HSV-I). Antibodies to HSV-I were detected in both intraocular fluids and sera of two cases, and in intraocular fluids alone in one case of ARN. Among 120 control patients undergoing routine intraocular surgery antibodies to HSV-I were detected in the sera of 85 (79.2%) but in the intraocular fluids of only two (1.7%). The presence of antibody within the eye may indicate local antibody production, antibody sequestration within the eye, or damage to the blood ocular barrier.

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Year:  1986        PMID: 3004557      PMCID: PMC1040924          DOI: 10.1136/bjo.70.2.81

Source DB:  PubMed          Journal:  Br J Ophthalmol        ISSN: 0007-1161            Impact factor:   4.638


  11 in total

1.  HERPES SIMPLEX RETINOPATHY IN AN INFANT.

Authors:  D G COGAN; T KUWABARA; G F YOUNG; D L KNOX
Journal:  Arch Ophthalmol       Date:  1964-11

2.  Immune complexes in the aqueous humor and serum.

Authors:  J P Dernouchamps; J P Vaerman; J Michiels; P L Masson
Journal:  Am J Ophthalmol       Date:  1977-07       Impact factor: 5.258

3.  Immunoglobulins and antinuclear antibodies in aqueous humour from patients with juvenile "rheumatoid" arthritis (Still's disease).

Authors:  A H Rahi; J J Kanski; A Fielder
Journal:  Trans Ophthalmol Soc U K       Date:  1977-04

4.  Antibody to Toxocara canis in the aqueous humor.

Authors:  N T Felberg; J A Shields; J L Federman
Journal:  Arch Ophthalmol       Date:  1981-09

5.  Bilateral acute retinal necrosis.

Authors:  N J Young; A C Bird
Journal:  Br J Ophthalmol       Date:  1978-09       Impact factor: 4.638

6.  Studies on the permeability of the blood-retinal barrier. I. On the existence, development, and site of a blood-retinal barrier.

Authors:  J G Cunha-Vaz; M Shakib; N Ashton
Journal:  Br J Ophthalmol       Date:  1966-08       Impact factor: 4.638

7.  Definitive serological diagnosis of ocular toxoplasmosis.

Authors:  G Desmonts
Journal:  Arch Ophthalmol       Date:  1966-12

8.  The acute retinal necrosis syndrome. Part 2: Histopathology and etiology.

Authors:  W W Culbertson; M S Blumenkranz; H Haines; D M Gass; K B Mitchell; E W Norton
Journal:  Ophthalmology       Date:  1982-12       Impact factor: 12.079

9.  Antibodies against Toxoplasma gondii in the aqueous humour of patients with active retinochoroiditis.

Authors:  O O Pedersen; A M Lorentzen-Styr
Journal:  Acta Ophthalmol (Copenh)       Date:  1981-10

10.  Vitrectomy and intravitreal antiviral drug therapy in acute retinal necrosis syndrome. Report of two cases.

Authors:  G A Peyman; M F Goldberg; E Uninsky; H Tessler; J Pulido; R Hendricks
Journal:  Arch Ophthalmol       Date:  1984-11
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  4 in total

1.  Acute retinal necrosis syndrome.

Authors:  D S Gartry; D J Spalton; A Tilzey; P G Hykin
Journal:  Br J Ophthalmol       Date:  1991-05       Impact factor: 4.638

2.  Specific antibody production in herpes keratitis: intraocular inflammation and corneal neovascularisation as predicting factors.

Authors:  Pierre-Yves Robert; Anja Liekfeld; Sylvia Metzner; Sylvie Ranger-Rogez; Jean-Paul Adenis; François Denis; Christian Hartmann; Uwe Pleyer
Journal:  Graefes Arch Clin Exp Ophthalmol       Date:  2005-07-26       Impact factor: 3.117

3.  Immunological analysis of the aqueous humour in candida endophthalmitis. I: Experimental study.

Authors:  F Malecaze; M H Bessieres; P Bec; S Fleutiaux; A Mathis; J P Seguela
Journal:  Br J Ophthalmol       Date:  1988-04       Impact factor: 4.638

Review 4.  Rational acyclovir therapy in herpetic eye disease.

Authors:  M G Falcon
Journal:  Br J Ophthalmol       Date:  1987-02       Impact factor: 4.638

  4 in total

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