Literature DB >> 30045091

A Novel Use of Trypan Blue During Canalicular Glaucoma Surgery to Identify Aqueous Outflow to Episcleral and Intrascleral Veins.

Daniel Laroche1, Andrea Nortey2, Chester Ng3.   

Abstract

PURPOSE: We describe a novel technique comprising the use of trypan blue to confirm aqueous outflow to collector channels and aqueous veins after goniotomy with the Kahook Dual Blade (New World Medical, Rancho Cucamonga, CA). Intraocular dyes have been safely used during ophthalmic surgery to evaluate the patency of the trabecular meshwork and collector channels. Further, trypan blue has been safely used to stain the anterior capsule of the lens in cataract surgery, to enhance visualization for capsulorhexis; similarly, trypan blue has been safely used to stain the trabecular meshwork for enhanced visualization during glaucoma angle surgery. Channelography enables evaluation of the collector channels during canaloplasty with fluorescein dye; episcleral fluid wave enables evaluation of the intraoperative structural patency of the conventional outflow system, from the anterior chamber to the episcleral and conjunctival distal collectors after Trabectome goniotomy (NeoMedix Corporation, Tustin, CA). PATIENTS AND METHODS: We evaluated 4 cases of glaucoma patients who underwent goniotomy with the Kahook Dual Blade to observe whether trypan blue could identify the patency of Schlemm's canal and aqueous egress to episcleral and intrascleral veins.
RESULTS: We successfully confirmed the outflow pathway via Schlemm's canal and collector channels with trypan blue in 3 of the 4 cases.
CONCLUSIONS: We conclude that trypan blue can be used safely to confirm both aqueous outflow and the patency of Schlemm's canal and aqueous veins during canalicular glaucoma surgery.

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Year:  2018        PMID: 30045091     DOI: 10.1097/IJG.0000000000001030

Source DB:  PubMed          Journal:  J Glaucoma        ISSN: 1057-0829            Impact factor:   2.503


  4 in total

Review 1.  Precision medicine to prevent glaucoma-related blindness.

Authors:  Sayoko E Moroi; David M Reed; David S Sanders; Ahmed Almazroa; Lawrence Kagemann; Neil Shah; Nakul Shekhawat; Julia E Richards
Journal:  Curr Opin Ophthalmol       Date:  2019-05       Impact factor: 3.761

2.  Aqueous Angiographic Outflow Improvement after Trabecular Microbypass in Glaucoma Patients.

Authors:  Alex S Huang; Rafaella C Penteado; Vahan Papoyan; Lilit Voskanyan; Robert N Weinreb
Journal:  Ophthalmol Glaucoma       Date:  2018-12-18

Review 3.  Aqueous outflow imaging techniques and what they tell us about intraocular pressure regulation.

Authors:  Jed A Lusthaus; Tasneem Z Khatib; Paul A R Meyer; Peter McCluskey; Keith R Martin
Journal:  Eye (Lond)       Date:  2020-08-21       Impact factor: 3.775

4.  Changes in the deep vasculature assessed using anterior segment OCT angiography following trabecular meshwork targeted minimally invasive glaucoma surgery.

Authors:  Yoko Okamoto; Tadamichi Akagi; Takanori Kameda; Kenji Suda; Masahiro Miyake; Hanako Ohashi Ikeda; Shogo Numa; Akitaka Tsujikawa
Journal:  Sci Rep       Date:  2022-10-13       Impact factor: 4.996

  4 in total

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