| Literature DB >> 30044897 |
Carolyne K Smith1, Giorgio Trinchieri1.
Abstract
The role of the microbiota in many diseases including cancer has gained increasing attention. Paired with this is our expanding appreciation for the heterogeneity of the neutrophil compartment regarding surface marker expression and functionality. In this review, we will discuss the influence of the microbiota on granulopoiesis and consequent activity of neutrophils in cancer. As evidence for this microbiota-neutrophil-cancer axis builds, it exposes new therapeutic targets to improve a cancer patient's outcome. ©2018 Society for Leukocyte Biology.Entities:
Keywords: TAN; cancer; granulopoiesis; microbiota; neutrophils
Mesh:
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Year: 2018 PMID: 30044897 DOI: 10.1002/JLB.4RI0418-151R
Source DB: PubMed Journal: J Leukoc Biol ISSN: 0741-5400 Impact factor: 4.962