Literature DB >> 3004482

Expression of aldolase A messenger RNAs in human adult and foetal tissues and in hepatoma.

F Mennecier, D Daegelen, F Schweighoffer, M Levin, A Kahn.   

Abstract

3 specific cDNA clones for human aldolase A were isolated from a human muscle library. One of them was subcloned in M 13 phage, then used as a probe to investigate the patterns and the levels of aldolase A mRNA in various human tissues. Two mRNA species differing in length were observed. The lighter one -1550 bases- was found specific to skeletal muscle; its amount increased during muscle development. The heavier aldolase A mRNA -1650 bases- accounted for foetal and ubiquitous presence of aldolase A isozyme. The resurgence of aldolase A in hepatomas occurred through this latter mRNA species.

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Year:  1986        PMID： 3004482     DOI： 10.1016/0006-291x(86)90363-3

Source DB:  PubMed          Journal:  Biochem Biophys Res Commun        ISSN： 0006-291X            Impact factor:   3.575


  5 in total

1.  A novel gene, the protein product of which is mainly expressed in germline cells and in the dorsal structures of Xenopus.

Authors:  Shinya Yamakita; Yuichiro Mishima; Kohji Ikenishi
Journal:  Dev Genes Evol       Date:  2004-01-28       Impact factor: 0.900

2.  Regulation of the multiple promoters of the human aldolase A gene: response of its two ubiquitous promoters to agents promoting cell proliferation.

Authors:  S Gautron; P Maire; V Hakim; A Kahn
Journal:  Nucleic Acids Res       Date:  1991-02-25       Impact factor: 16.971

3.  Localization of the active gene of aldolase on chromosome 16, and two aldolase A pseudogenes on chromosomes 3 and 10.

Authors:  S Serero; P Maire; V C Nguyen; O Cohen-Haguenauer; M S Gross; C Jégou-Foubert; M F de Tand; A Kahn; J Frézal
Journal:  Hum Genet       Date:  1988-02       Impact factor: 4.132

4.  Molecular mechanisms of McArdle's disease (muscle glycogen phosphorylase deficiency). RNA and DNA analysis.

Authors:  S Gautron; D Daegelen; F Mennecier; D Dubocq; A Kahn; J C Dreyfus
Journal:  J Clin Invest       Date:  1987-01       Impact factor: 14.808

5.  An opportunistic promoter sharing regulatory sequences with either a muscle-specific or a ubiquitous promoter in the human aldolase A gene.

Authors:  J P Concordet; M Salminen; J Demignon; C Moch; P Maire; A Kahn; D Daegelen
Journal:  Mol Cell Biol       Date:  1993-01       Impact factor: 4.272
  5 in total

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