Literature DB >> 3004464

Molecular cloning of rat mitochondrial glutamic oxaloacetic transaminase mRNA and regulation of its expression in regenerating liver.

Y Horio, R Sakakibara, T Tanaka, M Taketoshi, K Obaru, K Shimada, Y Morino, H Wada.   

Abstract

cDNA clones for rat mitochondrial glutamic oxaloacetic transaminase (mGOT) have been isolated from a rat liver cDNA library. One of the clones, designated p501, contained a cDNA insert of 1.4 kilobase pairs in length and hybridized to a mRNA of 2.4 kilobases from rat liver. We measured mGOT mRNA content in a regenerating rat liver. In a regenerating rat liver, mGOT activity was increased and reached maximum (170% of control activity) at about 48 h following the operation. Using the cDNA of mGOT, it was revealed that the increase of mGOT in the regenerating rat liver depended on its mRNA content.

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Year:  1986        PMID： 3004464     DOI： 10.1016/s0006-291x(86)80492-2

Source DB:  PubMed          Journal:  Biochem Biophys Res Commun        ISSN： 0006-291X            Impact factor:   3.575


  3 in total

1.  Molecular cloning and sequencing of a cDNA of rat dopa decarboxylase: partial amino acid homologies with other enzymes synthesizing catecholamines.

Authors:  T Tanaka; Y Horio; M Taketoshi; I Imamura; M Ando-Yamamoto; K Kangawa; H Matsuo; M Kuroda; H Wada
Journal:  Proc Natl Acad Sci U S A       Date:  1989-10       Impact factor: 11.205

2.  Quantitation of plasma membrane fatty acid-binding protein by enzyme dilution and monoclonal antibody based immunoassay.

Authors:  S L Zhou; B J Potter; D Stump; D Sorrentino; P D Berk
Journal:  Mol Cell Biochem       Date:  1990 Oct 15-Nov 8       Impact factor: 3.396

3.  Plasma membrane fatty acid-binding protein and mitochondrial glutamic-oxaloacetic transaminase of rat liver are related.

Authors:  P D Berk; H Wada; Y Horio; B J Potter; D Sorrentino; S L Zhou; L M Isola; D Stump; C L Kiang; S Thung
Journal:  Proc Natl Acad Sci U S A       Date:  1990-05       Impact factor: 11.205
  3 in total

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