Literature DB >> 30044129

Predictive biomarkers of chemotherapy-induced peripheral neuropathy: a review.

Patrick L Diaz1, Anthony Furfari1, Bo Angela Wan1, Henry Lam1, George Charames2,3,4,5, Leah Drost1, Angelo Fefekos6, Shannon Ohearn6, Alexia Blake6, Rashi Asthana1, Edward Chow1, Carlo DeAngelis1,7.   

Abstract

Chemotherapy-induced peripheral neuropathy (CIPN) is a common side effect of taxane treatment during chemotherapy. Identifying predictive biomarkers of CIPN would allow physicians to alter treatment given to patients according to a personal risk of developing this condition. The current literature on CIPN biomarkers is reviewed, identifying biomarkers which have been found to be significantly related to CIPN. Three genetic biomarkers are identified (ARHGEF10 rs9657362, CYP2C8 rs11572080/rs10509681 and FGD4 rs10771973) which have been found to act as predictive CIPN biomarkers in multiple studies. Possible mechanisms underlying the relationship between these single nucleotide polymorphisms and CIPN development are explored. The biomarkers identified in this study should be investigated further to generate predictive biomarkers that may be used in a clinical setting.

Entities:  

Keywords:  ARHGEF10; CIPN; CYP2C8; FGD4; chemotherapy-induced peripheral neuropathy; predictive biomarkers; taxane

Mesh：

Substances：

Year:  2018        PMID： 30044129     DOI： 10.2217/bmm-2017-0427

Source DB:  PubMed          Journal:  Biomark Med        ISSN： 1752-0363            Impact factor:   2.851


  6 in total

Review 1.  Chemotherapy-induced peripheral neuropathy: where are we now?

Authors:  Lesley A Colvin
Journal:  Pain       Date:  2019-05       Impact factor: 7.926

2.  Preclinical evidence for mitochondrial DNA as a potential blood biomarker for chemotherapy-induced peripheral neuropathy.

Authors:  Annalisa Trecarichi; Natalie A Duggett; Lucy Granat; Samantha Lo; Afshan N Malik; Lorena Zuliani-Álvarez; Sarah J L Flatters
Journal:  PLoS One       Date:  2022-01-11       Impact factor: 3.240

Review 3.  Cellular Pathogenesis of Chemotherapy-Induced Peripheral Neuropathy: Insights From Drosophila and Human-Engineered Skin Models.

Authors:  Grace Ji-Eun Shin; Hasan Erbil Abaci; Madison Christine Smith
Journal:  Front Pain Res (Lausanne)       Date:  2022-07-08

4.  Genetic polymorphism of pleiotrophin is associated with pain experience in Japanese adults: Case-control study.

Authors:  Kosuke Saita; Masahiko Sumitani; Daisuke Nishizawa; Takashi Tamura; Kazutaka Ikeda; Kenji Wakai; Yoshika Sudo; Hiroaki Abe; Jun Otonari; Hiroaki Ikezaki; Kenji Takeuchi; Asahi Hishida; Keitaro Tanaka; Chisato Shimanoe; Toshiro Takezaki; Rie Ibusuki; Isao Oze; Hidemi Ito; Etsuko Ozaki; Daisuke Matsui; Yohko Nakamura; Miho Kusakabe; Sadao Suzuki; Hiroko Nakagawa-Senda; Kokichi Arisawa; Sakurako Katsuura-Kamano; Kiyonori Kuriki; Yoshikuni Kita; Yasuyuki Nakamura; Yukihide Momozawa; Kanji Uchida
Journal:  Medicine (Baltimore)       Date:  2022-09-16       Impact factor: 1.817

5.  A Multimodal Approach to Discover Biomarkers for Taxane-Induced Peripheral Neuropathy (TIPN): A Study Protocol.

Authors:  Anukriti Sharma; Ken B Johnson; Bihua Bie; Emily E Rhoades; Alper Sen; Yuri Kida; Jennifer Hockings; Alycia Gatta; Jacqueline Davenport; Connie Arcangelini; Jennifer Ritzu; Jennifer DeVecchio; Ron Hughen; Mei Wei; G Thomas Budd; N Lynn Henry; Charis Eng; Joseph Foss; Daniel M Rotroff
Journal:  Technol Cancer Res Treat       Date:  2022 Jan-Dec

6.  Genetic Predictors of Chemotherapy-Induced Peripheral Neuropathy from Paclitaxel, Carboplatin and Oxaliplatin: NCCTG/Alliance N08C1, N08CA and N08CB Study.

Authors:  Araba A Adjei; Camden L Lopez; Daniel J Schaid; Jeff A Sloan; Jennifer G Le-Rademacher; Charles L Loprinzi; Aaron D Norman; Janet E Olson; Fergus J Couch; Andreas S Beutler; Celine M Vachon; Kathryn J Ruddy
Journal:  Cancers (Basel)       Date:  2021-03-03       Impact factor: 6.639
  6 in total

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