| Literature DB >> 30043722 |
Subha Nasir-Ahmad1, Rachael Cordina2, Gerald Liew3, Peter McCluskey4, David Celermajer1.
Abstract
In recent years, there has been a rise in the number patients with CHD surviving into adulthood. Many have complications related to their CHD or its treatments, outside the heart, including ocular abnormalities. The objective of this review is to highlight the ocular abnormalities that occur in adults with CHD, either from their condition or related to the common drugs prescribed to manage it. In particular, we reviewed the effects of cyanosis, coarctation of the aorta, endocarditis, and the side effects of Sildenafil and Amiodarone. A change in the retinal vasculature is a common observation with cyanosis or coarctation of the aorta. Occlusion of the retinal vessels may also be observed in cyanotic patients, as well as those with infectious endocarditis. Sildenafil has established ocular side effects; here they are explored in the context of therapy for pulmonary hypertension. Similarly, Amiodarone has established ocular risks, which are summarised. The high prevalence of ocular consequences in adult CHD patients reinforces the need for knowledge of the risks involved and for frequent ophthalmological screening where appropriate.Entities:
Keywords: Adult CHD; coarctation; cyanosis; endocarditis; ocular pathology
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Year: 2018 PMID: 30043722 DOI: 10.1017/S1047951118000859
Source DB: PubMed Journal: Cardiol Young ISSN: 1047-9511 Impact factor: 1.093