Literature DB >> 30043683

The green tea polyphenolic catechin epigallocatechin gallate and neuroprotection.

Ali Reza Khalatbary1, Emad Khademi1.   

Abstract

Epigallocatechin gallate is the most abundant composition of the tea catechins and is thought to be responsible for the majority of biological activity of green tea extracts such as antioxidant, anti-inflammatory, and antiapoptotic effects. Meanwhile, EGCG has been shown to be some of the neuroprotective effects against neural injuries and neurodegenerative diseases. This paper summarizes current knowledge on neuroprotective effects of EGCG and their molecular mechanisms responsible for the neuroprotection in various models of neurodegenerative and neural injury.

Entities:  

Keywords:  Epigallocatechin gallate; Neuroprotection; in vitro; in vivo

Mesh:

Substances:

Year:  2018        PMID: 30043683     DOI: 10.1080/1028415X.2018.1500124

Source DB:  PubMed          Journal:  Nutr Neurosci        ISSN: 1028-415X            Impact factor:   4.994


  11 in total

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