Kristiina Rönö1, Nora Elisabeth Grotenfelt2, Miira Marjuska Klemetti3,4,5, Beata Stach-Lempinen4, Emilia Huvinen3, Jelena Meinilä2, Anita Valkama2,6, Aila Tiitinen3, Risto Paavo Roine7,8,9, Maritta Pöyhönen-Alho3, Sture Andersson10, Hannele Laivuori5,11,12,13, Hannu Kautiainen2,14, Johan Gunnar Eriksson2,6,15, Saila Birgitta Koivusalo3. 1. Obstetrics and Gynecology, University of Helsinki and Helsinki University Hospital, Helsinki, Finland. kristiina.rono@helsinki.fi. 2. Unit of General Practice and Primary Health Care, University of Helsinki and Helsinki University Hospital, Helsinki, Finland. 3. Obstetrics and Gynecology, University of Helsinki and Helsinki University Hospital, Helsinki, Finland. 4. Obstetrics and Gynecology, South Karelia Central Hospital, Lappeenranta, Finland. 5. Medical and Clinical Genetics, University of Helsinki and Helsinki University Hospital, Helsinki, Finland. 6. Folkhälsan Research Center, Helsinki, Finland. 7. Department of Health and Social Management, Research Centre for Comparative Effectiveness and Patient Safety, University of Eastern Finland, Kuopio, Finland. 8. Kuopio University Hospital, Kuopio, Finland. 9. Administration, University of Helsinki and Helsinki University Hospital, Helsinki, Finland. 10. Children's Hospital, University of Helsinki and Helsinki University Hospital, Helsinki, Finland. 11. Institute for Molecular Medicine Finland, Helsinki Institute of Life Science, Helsinki, Finland. 12. Faculty of Medicine and Life Sciences, University of Tampere, Tampere, Finland. 13. Department of Obstetrics and Gynecology, Tampere University Hospital, Tampere, Finland. 14. General Practice and Primary Health Care, University of Eastern Finland, Kuopio, Finland. 15. Department of Chronic Disease Prevention, National Institute for Health and Welfare, Helsinki, Finland.
Abstract
OBJECTIVE: To assess the effect of lifestyle counseling on perinatal outcomes among women at high risk for gestational diabetes. STUDY DESIGN: A total of 492 women with obesity and/or prior gestational diabetes were allocated to intervention (four sessions of lifestyle counseling, n = 249) or usual care (n = 243) before 20 weeks' gestation. RESULT: Lifestyle indicators, gestational weight gain, or obstetric and perinatal outcomes did not differ between the two groups. An oral glucose tolerance test in the first half of pregnancy was pathological in 37.7% (n = 87/144) of intervention and 36.5% (n = 72/197) of control group women (p = 0.81). The total incidence of gestational diabetes diagnosed in the first or second half of pregnancy was 44.8% (107/239) in the intervention and 48.1% (111/231) in the control group (p = 0.48). CONCLUSIONS: The high prevalence of impaired glucose metabolism was observed already in early pregnancy, which may have contributed to the lack of effect of the intervention.
RCT Entities:
OBJECTIVE: To assess the effect of lifestyle counseling on perinatal outcomes among women at high risk for gestational diabetes. STUDY DESIGN: A total of 492 women with obesity and/or prior gestational diabetes were allocated to intervention (four sessions of lifestyle counseling, n = 249) or usual care (n = 243) before 20 weeks' gestation. RESULT: Lifestyle indicators, gestational weight gain, or obstetric and perinatal outcomes did not differ between the two groups. An oral glucose tolerance test in the first half of pregnancy was pathological in 37.7% (n = 87/144) of intervention and 36.5% (n = 72/197) of control group women (p = 0.81). The total incidence of gestational diabetes diagnosed in the first or second half of pregnancy was 44.8% (107/239) in the intervention and 48.1% (111/231) in the control group (p = 0.48). CONCLUSIONS: The high prevalence of impaired glucose metabolism was observed already in early pregnancy, which may have contributed to the lack of effect of the intervention.
Authors: Tamara den Harink; Nico A Blom; Reinoud J B J Gemke; Henk Groen; Annemieke Hoek; Ben W J Mol; Rebecca C Painter; Irene M Kuipers; Tessa J Roseboom; Arend W van Deutekom Journal: Int J Obes (Lond) Date: 2022-03-16 Impact factor: 5.551
Authors: Keith M Godfrey; Sheila J Barton; Sarah El-Heis; Timothy Kenealy; Heidi Nield; Philip N Baker; Yap Seng Chong; Wayne Cutfield; Shiao-Yng Chan Journal: Diabetes Care Date: 2021-03-29 Impact factor: 19.112
Authors: Malou D Menting; Cornelieke van de Beek; Kristiina Rono; Annemieke Hoek; Henk Groen; Rebecca C Painter; Polina Girchenko; Marius Lahti-Pulkkinen; Saila B Koivusalo; Katri Räikkönen; Johan G Eriksson; Tessa J Roseboom; Kati Heinonen Journal: Scand J Psychol Date: 2019-09-09