Literature DB >> 30042159

An Overview of PET Radiochemistry, Part 1: The Covalent Labels 18F, 11C, and 13N.

Verena Pichler1, Neydher Berroterán-Infante1, Cecile Philippe1, Chrysoula Vraka1, Eva-Maria Klebermass1, Theresa Balber1, Sarah Pfaff1, Lukas Nics1, Markus Mitterhauser1,2, Wolfgang Wadsak3,4.   

Abstract

This continuing educational article introduces the radiochemistry of PET tracers that exhibit a covalently bound radiolabel with the nuclides 11C, 13N, and 18F. The overall process of PET tracer production is explained, starting from the production of the radionuclide in a cyclotron; followed by the automatization process of the radiosynthesis, including the necessary steps for the respective synthesis; and finalized with the requirements for quality control.
© 2018 by the Society of Nuclear Medicine and Molecular Imaging.

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Year:  2018        PMID： 30042159     DOI： 10.2967/jnumed.117.190793

Source DB:  PubMed          Journal:  J Nucl Med        ISSN： 0161-5505            Impact factor:   10.057


  6 in total

Review 1.  The Chemical Scaffold of Theranostic Radiopharmaceuticals: Radionuclide, Bifunctional Chelator, and Pharmacokinetics Modifying Linker.

Authors:  Holis Abdul Holik; Faisal Maulana Ibrahim; Angela Alysia Elaine; Bernap Dwi Putra; Arifudin Achmad; Achmad Hussein Sundawa Kartamihardja
Journal:  Molecules       Date:  2022-05-10       Impact factor: 4.927

Review 2.  Update on PET Tracer Development for Muscarinic Acetylcholine Receptors.

Authors:  Marius Ozenil; Jonas Aronow; Marlon Millard; Thierry Langer; Wolfgang Wadsak; Marcus Hacker; Verena Pichler
Journal:  Pharmaceuticals (Basel)       Date:  2021-06-02

Review 3.  Advances in the In Vivo Molecular Imaging of Invasive Aspergillosis.

Authors:  Matthias Gunzer; Christopher R Thornton; Nicolas Beziere
Journal:  J Fungi (Basel)       Date:  2020-12-04

Review 4.  Experimental Nuclear Medicine Meets Tumor Biology.

Authors:  Theresa Balber; Loan Tran; Katarína Benčurová; Julia Raitanen; Gerda Egger; Markus Mitterhauser
Journal:  Pharmaceuticals (Basel)       Date:  2022-02-14

Review 5.  In vivo Imaging Technologies to Monitor the Immune System.

Authors:  Claire E McCarthy; Jordan M White; Nerissa T Viola; Heather M Gibson
Journal:  Front Immunol       Date:  2020-06-02       Impact factor: 8.786

Review 6.  Cellular and molecular imaging for stem cell tracking in neurological diseases.

Authors:  Xiaoxia Yang; De-Cai Tian; Wenyan He; Wei Lv; Junwan Fan; Haowen Li; Wei-Na Jin; Xia Meng
Journal:  Stroke Vasc Neurol       Date:  2020-10-29
  6 in total

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